Domains within Gallus gallus protein F1NVB5_CHICK (F1NVB5)

Nuclear receptor subfamily 5 group A member 2

Alternative representations: 1 /

Protein length501 aa
Source databaseUniProt
Identifiers F1NVB5_CHICK, F1NVB5, ENSGALP00000003413.5, ENSGALP00000003413, Q2WFZ8_CHICK, Q2WFZ8
Source gene ENSGALG00000002182
Alternative splicing F1NVB5_CHICK, A0A1D5PUH1_CHICK, A0A1D5PWF2_CHICK

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Metazoa

Predicted functional partners

F1NVB5_CHICK is shown as NR5A2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for NR5A2

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 13 PTMs annotated in this protein:

PTMCount
Phosphorylation5
SUMOylation3
Acetylation3
Methylation1
Ubiquitination1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein NR5A2.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 8996.ENSNMEP00000023721 in eggNOG.

OGTaxonomic classDescription
LKOG4218All organisms (root)steroidogenic factor 1,nuclear receptor subfamily 5 group A member 3,nuclear receptor subfamily 5 group A member 2
KOG4218Eukaryota (superkingdom)steroidogenic factor 1,nuclear receptor subfamily 5 group A member 3,nuclear receptor subfamily 5 group A member 2
HSW76Metazoa (kingdom)steroidogenic factor 1,nuclear receptor subfamily 5 group A member 3,nuclear receptor subfamily 5 group A member 2
942WHChordata (phylum)steroidogenic factor 1,nuclear receptor subfamily 5 group A member 2
5QC8NSarcopterygii (superclass)steroidogenic factor 1,nuclear receptor subfamily 5 group A member 2
6BD24Aves (class)nuclear receptor subfamily 5 group A member 2
8R8DYNeognathae (infraclass)nuclear receptor subfamily 5 group A member 2
BJ37ZGalloanserae (superorder)nuclear receptor subfamily 5 group A member 2
AIYG4Galliformes (order)nuclear receptor subfamily 5 group A member 2
9GQPKVertebrata (clade)steroidogenic factor 1,nuclear receptor subfamily 5 group A member 2
H4DIBBilateria (clade)steroidogenic factor 1,nuclear receptor subfamily 5 group A member 3,nuclear receptor subfamily 5 group A member 2
7MF86Opisthokonta (clade)steroidogenic factor 1,nuclear receptor subfamily 5 group A member 3,nuclear receptor subfamily 5 group A member 2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: