Domains within Polymorphum gilvum SL003B-26A1 protein F2IYS4_POLGS (F2IYS4)
Pyruvate dehydrogenase E1 component subunit alpha
Alternative representations: 1 /
| Protein length | 665 aa |
|---|---|
| Source database | UniProt |
| Identifiers | F2IYS4_POLGS, F2IYS4 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
Predicted functional partners
F2IYS4_POLGS is shown as 
pdhA-2 in the network
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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein F2IYS4_POLGS is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map01110 | Biosynthesis of secondary metabolites |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K11381 | bkdA | 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4] | iPath3 |
| K00166 | BCKDHA, bkdA1 | 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4] | iPath3 |
| K00162 | PDHB, pdhB | pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1] | iPath3 |
| K00161 | PDHA, pdhA | pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1] | iPath3 |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 991905.SL003B_1092 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG1071 | All organisms (root) | 2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4],pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1],acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha [EC:1.1.1.-] |
| LCOG0022 | All organisms (root) | pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1],2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:1.2.4.4],acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta [EC:1.1.1.-] |
| COG0022 | Bacteria (superkingdom) | pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1],2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:1.2.4.4],acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta [EC:1.1.1.-] |
| COG1071 | Bacteria (superkingdom) | pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1],2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4],acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha [EC:1.1.1.-] |
| 629MP | Proteobacteria (phylum) | pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1],2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4],acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha [EC:1.1.1.-] |
| 7ZCKM | Alphaproteobacteria (class) | 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4],acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta [EC:1.1.1.-],pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1] |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.