Domains within Pseudomonas mendocina NK-01 protein F4DWM8_PSEMN (F4DWM8)
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase
Alternative representations: 1 /
| Protein length | 715 aa |
|---|---|
| Source database | UniProt |
| Identifiers | F4DWM8_PSEMN, F4DWM8 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
Predicted functional partners
F4DWM8_PSEMN is shown as 
MDS_3949 in the network
Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.
The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein F4DWM8_PSEMN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map02020 | Two-component system | |
| map04112 | Cell cycle - Caulobacter | |
| map02025 | Biofilm formation - Pseudomonas aeruginosa |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K07708 | glnL, ntrB | two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] | |
| K03406 | mcp | methyl-accepting chemotaxis protein | |
| K07814 | K07814 | cyclic di-GMP phosphodiesterase [EC:3.1.4.-] | |
| K02488 | pleD | two-component system, cell cycle response regulator [EC:2.7.7.65] | |
| K21023 | mucR | diguanylate cyclase [EC:2.7.7.65] | |
| K07678 | barA, gacS, varS | two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3] |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 1001585.MDS_3949 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG3852 | All organisms (root) | two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3],two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3],two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3] |
| CBSPH | Pseudomonas aeruginosa group (species group) | Response_reg,GGDEF,EAL |
| LCOG3437 | All organisms (root) | cyclic di-GMP phosphodiesterase [EC:3.1.4.-],two-component system, response regulator RpfG,two-component system, chemotaxis family, chemotaxis protein CheY |
| LCOG5001 | All organisms (root) | diguanylate cyclase [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52],c-di-GMP phosphodiesterase Gmr [EC:3.1.4.52] |
| COG5001 | Bacteria (superkingdom) | diguanylate cyclase [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52],c-di-GMP phosphodiesterase Gmr [EC:3.1.4.52] |
| COG3437 | Bacteria (superkingdom) | cyclic di-GMP phosphodiesterase [EC:3.1.4.-],two-component system, response regulator RpfG,two-component system, chemotaxis family, chemotaxis protein CheY |
| COG3852 | Bacteria (superkingdom) | two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3],two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3],two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3] |
| 63FPC | Proteobacteria (phylum) | methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],two-component system, sensor histidine kinase [EC:2.7.13.3] |
| ESDPY | Gammaproteobacteria (class) | two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3],diguanylate cyclase [EC:2.7.7.65],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] |
| FEYBQ | Pseudomonadales (order) | two-component system, cell cycle response regulator [EC:2.7.7.65] |
| HA4NM | Pseudomonadaceae (family) | two-component system, cell cycle response regulator [EC:2.7.7.65] |
| 5CQ6U | Pseudomonas (genus) | two-component system, cell cycle response regulator [EC:2.7.7.65] |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.