Domains within Mus musculus protein IGLL1_MOUSE (P20764)

Immunoglobulin lambda-like polypeptide 1

Alternative representations: 1 /

Protein length209 aa
Source databaseUniProt
Identifiers IGLL1_MOUSE, P20764, ENSMUSP00000097713.3, ENSMUSP00000097713, E9QMX0, Q5W1K3, F7CFU6_MOUSE, F7CFU6
Source gene ENSMUSG00000075370

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

IGLL1_MOUSE is shown as Igll1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Igll1

Protein IGLL1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05340Primary immunodeficiency
map04514Cell adhesion molecules

KEGG orthologous groups

KONameDescription
K06553VPREB, CD179apre-B lymphocyte gene
K25874KIRREL, NEPHKirrel/Neph family protein
K06554IGLL1, IGLL, CD179bimmunoglobulin lambda-like polypeptide 1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 2 PTMs annotated in this protein:

PTMCount
Phosphorylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Igll1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000097713 in eggNOG.

OGTaxonomic classDescription
LKOG3510All organisms (root)Kirrel/Neph family protein,neural cell adhesion molecule,neurotrimin
KOG3510Eukaryota (superkingdom)Kirrel/Neph family protein,neural cell adhesion molecule,neurotrimin
HUQD5Metazoa (kingdom)pre-B lymphocyte gene,immunoglobulin lambda-like polypeptide 1,T cell receptor alpha chain V region
93P0GChordata (phylum)immunoglobulin lambda-like polypeptide 1,pre-B lymphocyte gene,T cell receptor alpha chain V region
5QF0DSarcopterygii (superclass)immunoglobulin lambda-like polypeptide 1,pre-B lymphocyte gene,T-box protein 6
8ZD1MMammalia (class)immunoglobulin lambda-like polypeptide 1
4RED9Euarchontoglires (superorder)immunoglobulin lambda-like polypeptide 1
AI8Q6Rodentia (order)immunoglobulin lambda-like polypeptide 1
8DCGAMyomorpha (suborder)immunoglobulin lambda-like polypeptide 1
7ISQZOpisthokonta (clade)pre-B lymphocyte gene,immunoglobulin lambda-like polypeptide 1,T cell receptor alpha chain V region
9FNBTVertebrata (clade)immunoglobulin lambda-like polypeptide 1,pre-B lymphocyte gene,KRAB domain-containing zinc finger protein
H4ZFRBilateria (clade)immunoglobulin lambda-like polypeptide 1,pre-B lymphocyte gene,T cell receptor alpha chain V region
CQ2CJMuridae (family)immunoglobulin lambda-like polypeptide 1
AE8NSMurinae (subfamily)immunoglobulin lambda-like polypeptide 1
5PV1SMus (genus)immunoglobulin lambda-like polypeptide 1
HEA5HMus (subgenus)immunoglobulin lambda-like polypeptide 1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: