Domains within Rattus norvegicus protein G3V6G6_RAT (G3V6G6)

Synaptotagmin-like 4, isoform CRA_a

Alternative representations: 1 /

Protein length672 aa
Source databaseUniProt
Identifiers G3V6G6_RAT, G3V6G6, ENSRNOP00000004909.3, ENSRNOP00000004909
Source gene ENSRNOG00000003526
Alternative splicing G3V6G6_RAT, D3ZTZ2_RAT

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Predicted functional partners

G3V6G6_RAT is shown as Sytl4 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Sytl4

Protein G3V6G6_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04721Synaptic vesicle cycle
map04714Thermogenesis

KEGG orthologous groups

KONameDescription
K17598SYTLsynaptotagmin-like protein

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 23 PTMs annotated in this protein:

PTMCount
Phosphorylation19
Acetylation4

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Sytl4.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000004909 in eggNOG.

OGTaxonomic classDescription
LKOG1028All organisms (root)synaptotagmin-like protein,synaptotagmin-14/16,synaptotagmin-1
KOG1028Eukaryota (superkingdom)synaptotagmin-like protein,synaptotagmin-14/16,synaptotagmin-1
HVMI3Metazoa (kingdom)synaptotagmin-like protein,NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
942DRChordata (phylum)synaptotagmin-like protein
5RB5ZSarcopterygii (superclass)synaptotagmin-like protein
8YVUVMammalia (class)synaptotagmin-like protein
4RGTREuarchontoglires (superorder)synaptotagmin-like protein
AIC46Rodentia (order)synaptotagmin-like protein
8D41EMyomorpha (suborder)synaptotagmin-like protein
H4UWABilateria (clade)synaptotagmin-like protein
9G01ZVertebrata (clade)synaptotagmin-like protein
7H9B5Opisthokonta (clade)synaptotagmin-like protein,NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]
CQ965Muridae (family)synaptotagmin-like protein
AE1GQMurinae (subfamily)synaptotagmin-like protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: