Domains within Cavia porcellus protein H0VGH2_CAVPO (H0VGH2)

Uncharacterized protein

Alternative representations: 1 /

Protein length485 aa
Source databaseUniProt
Identifiers H0VGH2_CAVPO, H0VGH2, ENSCPOP00000009212.3, ENSCPOP00000009212
Source gene ENSCPOG00000010259
Alternative splicing A0A286Y2Y8_CAVPO, H0VGH2_CAVPO, A0A286XSB7_CAVPO

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

H0VGH2_CAVPO is shown as LOC101788648 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for LOC101788648

Protein H0VGH2_CAVPO is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05202Transcriptional misregulation in cancer
map03022Basal transcription factors

KEGG orthologous groups

KONameDescription
K14651TAF15, NPL3transcription initiation factor TFIID subunit 15
K13098TLS, FUSRNA-binding protein FUS

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10141.ENSCPOP00000009212 in eggNOG.

OGTaxonomic classDescription
LKOG1995All organisms (root)RNA-binding protein FUS,RNA-binding protein EWS,transcription initiation factor TFIID subunit 15
KOG1995Eukaryota (superkingdom)RNA-binding protein FUS,RNA-binding protein EWS,transcription initiation factor TFIID subunit 15
HW3ZIMetazoa (kingdom)RNA-binding protein FUS,RNA-binding protein EWS,transcription initiation factor TFIID subunit 15
93S2QChordata (phylum)transcription initiation factor TFIID subunit 15,RNA-binding protein FUS,serine protease 27 [EC:3.4.21.-]
5RBKHSarcopterygii (superclass)transcription initiation factor TFIID subunit 15,RNA-binding protein FUS
8ZI28Mammalia (class)transcription initiation factor TFIID subunit 15
4RK8YEuarchontoglires (superorder)transcription initiation factor TFIID subunit 15
AIC2ERodentia (order)transcription initiation factor TFIID subunit 15
EVKIPHystricomorpha (suborder)transcription initiation factor TFIID subunit 15
9GNZFVertebrata (clade)transcription initiation factor TFIID subunit 15,RNA-binding protein FUS,serine protease 27 [EC:3.4.21.-]
7HZJYOpisthokonta (clade)RNA-binding protein FUS,RNA-binding protein EWS,transcription initiation factor TFIID subunit 15
H5F5FBilateria (clade)RNA-binding protein FUS,RNA-binding protein EWS,transcription initiation factor TFIID subunit 15

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: