Domains within Pongo abelii protein H2PX32_PONAB (H2PX32)

CNGA2 isoform 1

Alternative representations: 1 /

Protein length664 aa
Source databaseUniProt
Identifiers H2PX32_PONAB, H2PX32, ENSPPYP00000023309.1, ENSPPYP00000023309
Source gene ENSPPYG00000020824

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

H2PX32_PONAB is shown as CNGA2 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CNGA2

Protein H2PX32_PONAB is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04024cAMP signaling pathway

KEGG orthologous groups

KONameDescription
K04949CNGA2cyclic nucleotide gated channel alpha 2
K04950CNGA3cyclic nucleotide gated channel alpha 3

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9601.ENSPPYP00000023309 in eggNOG.

OGTaxonomic classDescription
LKOG0500All organisms (root)cyclic nucleotide gated channel alpha 3,cyclic nucleotide gated channel alpha 2,cyclic nucleotide gated channel alpha 1
KOG0500Eukaryota (superkingdom)cyclic nucleotide gated channel alpha 3,cyclic nucleotide gated channel alpha 2,cyclic nucleotide gated channel alpha 1
HU7HMMetazoa (kingdom)cyclic nucleotide gated channel alpha 3,cyclic nucleotide gated channel alpha 2,cyclic nucleotide gated channel alpha 1
94PJQChordata (phylum)cyclic nucleotide gated channel alpha 2,cyclic nucleotide gated channel alpha 1,cyclic nucleotide gated channel alpha 4
5R1GXSarcopterygii (superclass)cyclic nucleotide gated channel alpha 2
8ZBPWMammalia (class)cyclic nucleotide gated channel alpha 2
4R631Euarchontoglires (superorder)cyclic nucleotide gated channel alpha 2
4ZNP9Primates (order)cyclic nucleotide gated channel alpha 2
98KIPHaplorrhini (suborder)cyclic nucleotide gated channel alpha 2
BUZYHSimiiformes (infraorder)cyclic nucleotide gated channel alpha 2
9EYBZCatarrhini (parvorder)cyclic nucleotide gated channel alpha 2
H3PQVBilateria (clade)cyclic nucleotide gated channel alpha 3,cyclic nucleotide gated channel alpha 2,cyclic nucleotide gated channel alpha 1
9GNZSVertebrata (clade)cyclic nucleotide gated channel alpha 2,cyclic nucleotide gated channel alpha 1,cyclic nucleotide gated channel alpha 4
7JXY4Opisthokonta (clade)cyclic nucleotide gated channel alpha 3,cyclic nucleotide gated channel alpha 2,cyclic nucleotide gated channel alpha 1
FX54HHominoidea (superfamily)cyclic nucleotide gated channel alpha 2
5N5FHHominidae (family)cyclic nucleotide gated channel alpha 2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: