Domains within Mycobacterium tuberculosis CDC1551 protein CRPL_MYCTO (P9WMH2)

CRP-like cAMP-activated global transcriptional regulator

Alternative representations: 1 /

Protein length224 aa
Source databaseUniProt
Identifiers F2GFB8, L0TDH2, O69644, Q7D534, CRPL_MYCTU, P9WMH3, A0A045H6U0_MYCTX, A0A045H6U0, A0A083VRF6_MYCBI, A0A083VRF6, M8C8Q0_9MYCO, M8C8Q0, A0A197J2P8_9MYCO, A0A197J2P8, A0A120J3E1_9MYCO, A0A120J3E1, A5U900_MYCTA, A5U900, I6Y496_MYCTU, I6Y496, A0A0H3LGG9_MYCTE, A0A0H3LGG9, A0A120IYV2_9MYCO, A0A120IYV2, A0A1R3Y4Y5_MYCBO, A0A1R3Y4Y5, A0A1S1B6L8_9MYCO, A0A1S1B6L8, F8M901_MYCA0, F8M901, R4MNS6_MYCTX, R4MNS6, CRPL_MYCTO, P9WMH2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

CRPL_MYCTO is shown as crp in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for crp

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 115862.BBG46_19080 in eggNOG.

OGTaxonomic classDescription
LCOG0664All organisms (root)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein,CRP/FNR family transcriptional regulator, anaerobic regulatory protein,cAMP-dependent protein kinase regulator
GJV6XMycobacterium tuberculosis complex (species group)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
COG0664Bacteria (superkingdom)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein,CRP/FNR family transcriptional regulator, anaerobic regulatory protein,CRP/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator
68UQKActinobacteria (phylum)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein,CRP/FNR family transcriptional regulator, nitrogen oxide reductase regulator,CRP/FNR family transcriptional regulator, anaerobic regulatory protein
FBCXUActinomycetia (class)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein,CRP/FNR family transcriptional regulator, nitrogen oxide reductase regulator,CRP/FNR family transcriptional regulator, anaerobic regulatory protein
EMIRPCorynebacteriales (order)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein,CRP/FNR family transcriptional regulator, cAMP and macrophage regulator
58EVPMycobacteriaceae (family)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
HMZW7Mycobacterium (genus)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
EKA1SMycobacterium tuberculosis (species)CRP/FNR family transcriptional regulator, cyclic AMP receptor protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: