Domains within Mycobacterium tuberculosis CDC1551 protein HRP1_MYCTO (P9WJA2)

Hypoxic response protein 1

Alternative representations: 1 /

Protein length143 aa
Source databaseUniProt
Identifiers F8M2Y0, L0TBT6, O06186, Q7D6V4, A0A2I6B2H4_9BETA, A0A2I6B2H4, HRP1_MYCTU, P9WJA3, A0A045JJ98_MYCTX, A0A045JJ98, A0A1A9EA25_MYCBI, A0A1A9EA25, M8CK81_9MYCO, M8CK81, A0A0K2HZQ1_MYCBI, A0A0K2HZQ1, A0A109SYY4_9MYCO, A0A109SYY4, A5U5X7_MYCTA, A5U5X7, I6Y193_MYCTU, I6Y193, A0A0H3LCG1_MYCTE, A0A0H3LCG1, A0A109SQ13_9MYCO, A0A109SQ13, A0A1R3Y200_MYCBO, A0A1R3Y200, A0A1S1BGL2_9MYCO, A0A1S1BGL2, F8M2Y0_MYCA0, G0TQM6_MYCCP, G0TQM6, A0A0H3MG08_MYCBP, A0A0H3MG08, R4MKS0_MYCTX, R4MKS0, A0A0T9FL28_MYCTX, A0A0T9FL28, HRP1_MYCTO, P9WJA2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

HRP1_MYCTO is shown as hrp1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for hrp1

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 115862.BBG46_13770 in eggNOG.

OGTaxonomic classDescription
GJWS4Mycobacterium tuberculosis complex (species group)CBS
LCOG2905All organisms (root)arabinose-5-phosphate isomerase [EC:5.3.1.13],CBS domain-containing protein,IMP dehydrogenase [EC:1.1.1.205]
COG2905Bacteria (superkingdom)arabinose-5-phosphate isomerase [EC:5.3.1.13],CBS domain-containing protein,IMP dehydrogenase [EC:1.1.1.205]
699RGActinobacteria (phylum)CBS domain-containing protein
FAVB2Actinomycetia (class)CBS domain-containing protein
ENEHPCorynebacteriales (order)CBS
58XPUMycobacteriaceae (family)CBS
HMKFTMycobacterium (genus)CBS
EK8H7Mycobacterium tuberculosis (species)CBS

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: