Domains within Schizosaccharomyces pombe 972h- protein SUCA_SCHPO (O13750)

Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial

Alternative representations: 1 /

Protein length331 aa
Source databaseUniProt
Identifiers SUCA_SCHPO, O13750

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

SUCA_SCHPO is shown as SPAC16E8.17c in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SPAC16E8.17c

Protein SUCA_SCHPO is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map00020Citrate cycle (TCA cycle) iPath3
Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

KONameDescription
K01902sucDsuccinyl-CoA synthetase alpha subunit [EC:6.2.1.5] iPath3
K01899LSC1succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5] iPath3
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 9 PTMs annotated in this protein:

PTMCount
Phosphorylation6
Acetylation2
Ubiquitination1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein SPAC16E8.17c.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 284812.O13750 in eggNOG.

OGTaxonomic classDescription
FR5J2Dikarya (subkingdom)succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5]
LCOG0074All organisms (root)succinyl-CoA synthetase alpha subunit [EC:6.2.1.5],succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5],FdrA protein
KOG1255Eukaryota (superkingdom)succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5],phosphatidate phosphatase [EC:3.1.3.4],nuclear pore complex protein Nup214
BM28IFungi (kingdom)succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5]
9S1VDAscomycota (phylum)succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5]
DVGG9Taphrinomycotina (subphylum)succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5]
7NEQYOpisthokonta (clade)succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5],phosphatidate phosphatase [EC:3.1.3.4],nuclear pore complex protein Nup214
CE5FRSchizosaccharomyces (genus)succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: