Domains within Homo sapiens protein KIF3B_HUMAN (O15066)

Kinesin-like protein KIF3B

Alternative representations: 1 /

Protein length747 aa
Source databaseUniProt
Identifiers KIF3B_HUMAN, O15066, ENSP00000364864.3, ENSP00000364864, B2RMP4, B4DSR5, E1P5M5, H2QK62_PANTR, H2QK62, A0A2K5L083_CERAT, A0A2K5L083, A0A096NUY3_PAPAN, A0A096NUY3, A0A2K5INE6_COLAP, A0A2K5INE6, H9F219_MACMU, H9F219
Source gene ENSG00000101350

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

KIF3B_HUMAN is shown as KIF3B in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for KIF3B

Protein KIF3B_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04340Hedgehog signaling pathway

KEGG orthologous groups

KONameDescription
K20196KIF3Bkinesin family member 3B
K10400KIF15kinesin family member 15

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 66 PTMs annotated in this protein:

PTMCount
Phosphorylation48
Acetylation16
Ubiquitination2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein KIF3B.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000364864 in eggNOG.

OGTaxonomic classDescription
LKOG4280All organisms (root)kinesin family member 15,kinesin family member 26,kinesin family member 6/9
KOG4280Eukaryota (superkingdom)kinesin family member 15,kinesin family member 26,kinesin family member 6/9
HUP9DMetazoa (kingdom)kinesin family member 3B,kinesin family member 3A,kinesin family member 3C
94G1FChordata (phylum)kinesin family member 3C,kinesin family member 3B
5QS4ASarcopterygii (superclass)kinesin family member 3C,kinesin family member 3B
8ZAPMMammalia (class)kinesin family member 3C,kinesin family member 3B
4R6U2Euarchontoglires (superorder)kinesin family member 3B
4ZPFYPrimates (order)kinesin family member 3B
98DFEHaplorrhini (suborder)kinesin family member 3B
BVJ8XSimiiformes (infraorder)kinesin family member 3B
9EIFVCatarrhini (parvorder)kinesin family member 3B
7MNFUOpisthokonta (clade)kinesin family member 3B,kinesin family member 3A,kinesin family member 3C
9FGU3Vertebrata (clade)kinesin family member 3C,kinesin family member 3B
H53ARBilateria (clade)kinesin family member 3B,kinesin family member 3A,kinesin family member 3C
FX4GWHominoidea (superfamily)kinesin family member 3B
5MZI6Hominidae (family)kinesin family member 3B
5Y7TSHomininae (subfamily)kinesin family member 3B

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: