Domains within Caenorhabditis elegans protein O18302_CAEEL (O18302)

GOlgi-associated PDZ and Coiled-coil motif protein

Alternative representations: 1 /

Protein length414 aa
Source databaseUniProt
Identifiers ZK849.2A, O18302_CAEEL, O18302
Source gene WBGene00014101
Alternative splicing O18302_CAEEL, Q564T0_CAEEL, A5JYY2_CAEEL

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

O18302_CAEEL is shown as gopc-1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for gopc-1

Protein O18302_CAEEL is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04530Tight junction

KEGG orthologous groups

KONameDescription
K10692LNX1_2ligand of Numb protein X 1/2 [EC:2.3.2.27]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 8 PTMs annotated in this protein:

PTMCount
Phosphorylation5
Acetylation2
Ubiquitination1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ZK849.2.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 6239.ZK849.2a.1 in eggNOG.

OGTaxonomic classDescription
LKOG3528All organisms (root)ligand of Numb protein X 1/2 [EC:2.3.2.27],syntenin-1,intraflagellar transport protein 20
KOG3528Eukaryota (superkingdom)ligand of Numb protein X 1/2 [EC:2.3.2.27],syntenin-1,intraflagellar transport protein 20
HUE6TMetazoa (kingdom)golgi-associated PDZ and coiled-coil motif-containing protein
8BCMFNematoda (phylum)golgi-associated PDZ and coiled-coil motif-containing protein
HCVDRChromadorea (class)golgi-associated PDZ and coiled-coil motif-containing protein
6DUXPRhabditida (order)golgi-associated PDZ and coiled-coil motif-containing protein
8PYG2Rhabditina (suborder)golgi-associated PDZ and coiled-coil motif-containing protein
7KZDMOpisthokonta (clade)golgi-associated PDZ and coiled-coil motif-containing protein
H71F9Bilateria (clade)golgi-associated PDZ and coiled-coil motif-containing protein
AYGWPRhabditidae (family)golgi-associated PDZ and coiled-coil motif-containing protein
BT762Caenorhabditis (genus)golgi-associated PDZ and coiled-coil motif-containing protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: