Domains within Helicobacter pylori 26695 protein HCPA_HELPY (O25001)

Beta-lactamase HcpA

Alternative representations: 1 /

Protein length250 aa
Source databaseUniProt
Identifiers O32634, O85223, A0A2J9KKH8_HELPX, A0A2J9KKH8, A0A1Y3DZF8_HELPX, A0A1Y3DZF8, HCPA_HELPY, O25001

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

HCPA_HELPY is shown as hcpA in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for hcpA

Protein HCPA_HELPY is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04141Protein processing in endoplasmic reticulum
map04112Cell cycle - Caulobacter
map04714Thermogenesis

KEGG orthologous groups

KONameDescription
K07126K07126uncharacterized protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 85962.HP_0211 in eggNOG.

OGTaxonomic classDescription
LCOG0790All organisms (root)uncharacterized protein,SEL1 protein,cytochrome c oxidase assembly factor 7
COG0790Bacteria (superkingdom)uncharacterized protein,localization factor PodJL,exopolysaccharide production negative regulator
616RZProteobacteria (phylum)uncharacterized protein,alginate biosynthesis protein AlgK,localization factor PodJL
A1S1Rdelta/epsilon subdivisions (subphylum)uncharacterized protein,cytochrome c oxidase assembly factor 7
840DCEpsilonproteobacteria (class)uncharacterized protein,cytochrome c oxidase assembly factor 7
DX5W5Campylobacterales (order)uncharacterized protein
BYS0CHelicobacteraceae (family)uncharacterized protein
7TPSBHelicobacter (genus)uncharacterized protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: