Domains within Helicobacter pylori 26695 protein Y745_HELPY (O25441)

Uncharacterized RNA pseudouridine synthase HP_0745

Alternative representations: 1 /

Protein length327 aa
Source databaseUniProt
Identifiers A0A2J9KJ23_HELPX, A0A2J9KJ23, A0A1Y3E677_HELPX, A0A1Y3E677, Y745_HELPY, O25441

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

Y745_HELPY is shown as HP_0745 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for HP_0745

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 85962.HP_0745 in eggNOG.

OGTaxonomic classDescription
LCOG0564All organisms (root)23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23],tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29],23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]
COG0564Bacteria (superkingdom)23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23],tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29],23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]
61N94Proteobacteria (phylum)23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23],tRNA pseudouridine65 synthase [EC:5.4.99.26],23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]
A1U3Qdelta/epsilon subdivisions (subphylum)23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
83T5AEpsilonproteobacteria (class)23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
DX7PDCampylobacterales (order)23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
BYW0PHelicobacteraceae (family)23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
7TP75Helicobacter (genus)23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: