Domains within Helicobacter pylori 26695 protein MFD_HELPY (O26066)

Transcription-repair-coupling factor

Alternative representations: 1 /

Protein length999 aa
Source databaseUniProt
Identifiers A0A2J9KL41_HELPX, A0A2J9KL41, A0A1Y3DYP1_HELPX, A0A1Y3DYP1, MFD_HELPY, O26066

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

MFD_HELPY is shown as mfd in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for mfd

Protein MFD_HELPY is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03420Nucleotide excision repair

KEGG orthologous groups

KONameDescription
K03723mfdtranscription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 85962.HP_1541 in eggNOG.

OGTaxonomic classDescription
LCOG1197All organisms (root)transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4],primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4],excinuclease ABC subunit B
COG1197Bacteria (superkingdom)transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4],primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4],excinuclease ABC subunit B
5YJSNProteobacteria (phylum)transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
A26HUdelta/epsilon subdivisions (subphylum)transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
83T5BEpsilonproteobacteria (class)transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
DX4FNCampylobacterales (order)transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
BYSUVHelicobacteraceae (family)transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
7TNZQHelicobacter (genus)transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: