Domains within Mus musculus protein GFRA3_MOUSE (O35118)

GDNF family receptor alpha-3

Alternative representations: 1 /

Protein length397 aa
Source databaseUniProt
Identifiers GFRA3_MOUSE, O35118, ENSMUSP00000025224.7, ENSMUSP00000025224, O35325, O55243, Q6NZC2, Q8C8L9
Source gene ENSMUSG00000024366

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

GFRA3_MOUSE is shown as Gfra3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Gfra3

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000025224 in eggNOG.

OGTaxonomic classDescription
6WD6GAll organisms (root)GDNF family receptor alpha,GDNF family receptor alpha-like
5JKIGEukaryota (superkingdom)GDNF family receptor alpha,GDNF family receptor alpha-like
HSTYSMetazoa (kingdom)GDNF family receptor alpha
93UB0Chordata (phylum)GDNF family receptor alpha
5QEKJSarcopterygii (superclass)GDNF family receptor alpha
8ZFJNMammalia (class)GDNF family receptor alpha
4RET5Euarchontoglires (superorder)GDNF family receptor alpha
AHXENRodentia (order)GDNF family receptor alpha
8DCJ4Myomorpha (suborder)GDNF family receptor alpha
H3BYRBilateria (clade)GDNF family receptor alpha
7JQU9Opisthokonta (clade)GDNF family receptor alpha
9GJJTVertebrata (clade)GDNF family receptor alpha
CQ00XMuridae (family)GDNF family receptor alpha
ADZ3EMurinae (subfamily)GDNF family receptor alpha
5PTZWMus (genus)GDNF family receptor alpha
HE084Mus (subgenus)GDNF family receptor alpha

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: