Domains within Mus musculus protein FGF15_MOUSE (O35622)

Fibroblast growth factor 15

Alternative representations: 1 /

Protein length218 aa
Source databaseUniProt
Identifiers FGF15_MOUSE, O35622, ENSMUSP00000033389.5, ENSMUSP00000033389, Q790L8_MOUSE, Q790L8
Source gene ENSMUSG00000031073
Alternative splicing FGF15_MOUSE, A0A140LIL5_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

FGF15_MOUSE is shown as Fgf15 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Fgf15

Protein FGF15_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05224Breast cancer
map04020Calcium signaling pathway

KEGG orthologous groups

KONameDescription
K04358FGFfibroblast growth factor
K22603FGF19fibroblast growth factor 19

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000033389 in eggNOG.

OGTaxonomic classDescription
LKOG3885All organisms (root)fibroblast growth factor,fibroblast growth factor 11/12/13,fibroblast growth factor 1
KOG3885Eukaryota (superkingdom)fibroblast growth factor,fibroblast growth factor 11/12/13,fibroblast growth factor 1
HT5XEMetazoa (kingdom)fibroblast growth factor 19,fibroblast growth factor 23
94G8AChordata (phylum)fibroblast growth factor 19
5QWW4Sarcopterygii (superclass)fibroblast growth factor 19
8ZHRYMammalia (class)fibroblast growth factor 19
4R2XFEuarchontoglires (superorder)fibroblast growth factor 19
AI9P9Rodentia (order)fibroblast growth factor 19
8D4HTMyomorpha (suborder)fibroblast growth factor 19
9FJQ2Vertebrata (clade)fibroblast growth factor 19
7NG88Opisthokonta (clade)fibroblast growth factor 19,fibroblast growth factor 23
H4EKDBilateria (clade)fibroblast growth factor 19,fibroblast growth factor 23
CQFFQMuridae (family)fibroblast growth factor 19
AE1FNMurinae (subfamily)fibroblast growth factor 19
5PQWXMus (genus)fibroblast growth factor 19
HECX3Mus (subgenus)fibroblast growth factor 19

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: