Domains within Mus musculus protein REPS1_MOUSE (O54916)

RalBP1-associated Eps domain-containing protein 1

Alternative representations: 1 /

Protein length795 aa
Source databaseUniProt
Identifiers REPS1_MOUSE, O54916, ENSMUSP00000123238.1, ENSMUSP00000123238, Q3UAM3, Q5PPQ9, Q8C9J9, Q99LR8, O54916-4
Source gene ENSMUSG00000019854
Alternative splicing D3Z2E3_MOUSE, D6RIN6_MOUSE, REPS1_MOUSE, A0A1L1SRE4_MOUSE, F6R6F1_MOUSE, F6YT69_MOUSE, F7AB82_MOUSE, A0A1L1SQL9_MOUSE, E9Q632_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Fungi/Metazoa group

Predicted functional partners

REPS1_MOUSE is shown as Reps1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Reps1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 41 PTMs annotated in this protein:

PTMCount
Phosphorylation39
Acetylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Reps1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000123238 in eggNOG.

OGTaxonomic classDescription
LKOG1955All organisms (root)RalBP1-associated Eps domain-containing protein
KOG1955Eukaryota (superkingdom)RalBP1-associated Eps domain-containing protein
HUC0JMetazoa (kingdom)RalBP1-associated Eps domain-containing protein
941YZChordata (phylum)RalBP1-associated Eps domain-containing protein
5QSITSarcopterygii (superclass)RalBP1-associated Eps domain-containing protein
8Z3TJMammalia (class)RalBP1-associated Eps domain-containing protein
4R87BEuarchontoglires (superorder)RalBP1-associated Eps domain-containing protein
AIDRPRodentia (order)RalBP1-associated Eps domain-containing protein
8DB7RMyomorpha (suborder)RalBP1-associated Eps domain-containing protein
7INH8Opisthokonta (clade)RalBP1-associated Eps domain-containing protein
H5YKNBilateria (clade)RalBP1-associated Eps domain-containing protein
9GD3SVertebrata (clade)RalBP1-associated Eps domain-containing protein
CQAMRMuridae (family)RalBP1-associated Eps domain-containing protein
AE0X4Murinae (subfamily)RalBP1-associated Eps domain-containing protein
5PUM2Mus (genus)RalBP1-associated Eps domain-containing protein
HEE2FMus (subgenus)RalBP1-associated Eps domain-containing protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: