Domains within Schizosaccharomyces pombe 972h- protein PUR8_SCHPO (O60105)
Adenylosuccinate lyase
Alternative representations: 1 /
| Protein length | 482 aa |
|---|---|
| Source database | UniProt |
| Identifiers | PUR8_SCHPO, O60105 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
Predicted functional partners
PUR8_SCHPO is shown as 
ade8 in the network
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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein PUR8_SCHPO is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map00250 | Alanine, aspartate and glutamate metabolism | iPath3 |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K01756 | purB, ADSL | adenylosuccinate lyase [EC:4.3.2.2] | iPath3 |
Post-translational modifications
PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 11 PTMs annotated in this protein:
| PTM | Count | |
|---|---|---|
 | Phosphorylation | 5 |
 | Ubiquitination | 5 |
 | Acetylation | 1 |
To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ade8.
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 284812.O60105 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| FQ1MA | Dikarya (subkingdom) | adenylosuccinate lyase [EC:4.3.2.2],3-carboxy-cis,cis-muconate cycloisomerase [EC:5.5.1.2],trans-aconitate decarboxylase [EC:4.1.1.113] |
| LCOG0015 | All organisms (root) | adenylosuccinate lyase [EC:4.3.2.2],3-carboxy-cis,cis-muconate cycloisomerase [EC:5.5.1.2],nitrosuccinate lyase [EC:4.3.99.5] |
| KOG2700 | Eukaryota (superkingdom) | adenylosuccinate lyase [EC:4.3.2.2],3-carboxy-cis,cis-muconate cycloisomerase [EC:5.5.1.2],trinucleotide repeat-containing gene 6 protein |
| BP61S | Fungi (kingdom) | adenylosuccinate lyase [EC:4.3.2.2],3-carboxy-cis,cis-muconate cycloisomerase [EC:5.5.1.2],trans-aconitate decarboxylase [EC:4.1.1.113] |
| 9SS6S | Ascomycota (phylum) | adenylosuccinate lyase [EC:4.3.2.2],3-carboxy-cis,cis-muconate cycloisomerase [EC:5.5.1.2] |
| DVDDS | Taphrinomycotina (subphylum) | adenylosuccinate lyase [EC:4.3.2.2] |
| 7JB9F | Opisthokonta (clade) | adenylosuccinate lyase [EC:4.3.2.2],3-carboxy-cis,cis-muconate cycloisomerase [EC:5.5.1.2],trinucleotide repeat-containing gene 6 protein |
| CE2SP | Schizosaccharomyces (genus) | adenylosuccinate lyase [EC:4.3.2.2] |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.