Domains within Drosophila melanogaster protein COPB2_DROME (O62621)

Coatomer subunit beta'

Alternative representations: 1 /

Protein length914 aa
Source databaseUniProt
Identifiers COPB2_DROME, O62621, FBPP0080048, Q3KN33, Q8MRM3, Q9VJZ0
Source gene FBgn0025724

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

COPB2_DROME is shown as beta'COP in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for beta'COP

Protein COPB2_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05171Coronavirus disease - COVID-19

KEGG orthologous groups

KONameDescription
K17302COPB2, SEC27coatomer subunit beta'

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 20 PTMs annotated in this protein:

PTMCount
Phosphorylation10
Ubiquitination7
Acetylation3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein beta'Cop.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0080048 in eggNOG.

OGTaxonomic classDescription
FUXP8melanogaster group (species group)coatomer subunit beta'
EIBUREndopterygota (cohort)coatomer subunit beta'
FE3QVmelanogaster subgroup (species subgroup)coatomer subunit beta'
LKOG0276All organisms (root)coatomer subunit beta',protein SYS1,zinc finger protein castor
KOG0276Eukaryota (superkingdom)coatomer subunit beta',protein SYS1,zinc finger protein castor
HVH3IMetazoa (kingdom)coatomer subunit beta'
HIQCZArthropoda (phylum)coatomer subunit beta'
85VXKHexapoda (subphylum)coatomer subunit beta'
AH8WFNeoptera (infraclass)coatomer subunit beta'
ANK7JDiptera (order)coatomer subunit beta'
7KWN2Opisthokonta (clade)coatomer subunit beta',zinc finger protein castor
H46I3Bilateria (clade)coatomer subunit beta'
EH5K1Drosophila (genus)coatomer subunit beta'
50EHPSophophora (subgenus)coatomer subunit beta'

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: