Domains within Bacillus subtilis subsp. subtilis str. 168 protein NRDEB_BACSU (O31875)
Ribonucleoside-diphosphate reductase NrdEB subunit alpha
Alternative representations: 1 /
| Protein length | 1084 aa |
|---|---|
| Source database | UniProt |
| Identifiers | Q7BVQ5, NRDEB_BPSPB, O64173, A0A164VKJ5_BACIU, A0A164VKJ5, Q5DVN8_BACIU, Q5DVN8, Q93L74_9BACI, Q93L74, NRDEB_BACSU, O31875 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
This domain architecture was probably invented with the emergence of cellular organisms
Predicted functional partners
NRDEB_BACSU is shown as 
nrdEB in the network
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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein NRDEB_BACSU is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map00240 | Pyrimidine metabolism | iPath3 |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K02314 | dnaB | replicative DNA helicase [EC:5.6.2.3] | |
| K00525 | E1.17.4.1A, nrdA, nrdE | ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] | iPath3 |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 224308.BSU20060 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG1372 | All organisms (root) | replicative DNA helicase [EC:5.6.2.3],ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1],ribonucleotide reductase, class II [EC:1.17.4.2] |
| LCOG0209 | All organisms (root) | ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1],ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1],ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2] |
| COG1372 | Bacteria (superkingdom) | replicative DNA helicase [EC:5.6.2.3],ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1],ribonucleotide reductase, class II [EC:1.17.4.2] |
| COG0209 | Bacteria (superkingdom) | ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1],ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2] |
| 9Y1RJ | Firmicutes (phylum) | ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] |
| G4YK8 | Bacilli (class) | ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] |
| F27CA | Bacillales (order) | ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] |
| F66WS | Bacillaceae (family) | ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] |
| AAJ1S | Bacillus (genus) | ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.