Domains within Aquifex aeolicus VF5 protein O67146_AQUAE (O67146)
Formate dehydrogenase alpha subunit
Alternative representations: 1 /
| Protein length | 1015 aa |
|---|---|
| Source database | UniProt |
| Identifiers | O67146_AQUAE, O67146 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
Predicted functional partners
O67146_AQUAE is shown as 
fdoG in the network
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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein O67146_AQUAE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG pathways
| Pathway | Description | |
|---|---|---|
| map00630 | Glyoxylate and dicarboxylate metabolism | iPath3 |
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K00123 | fdoG, fdhF, fdwA | formate dehydrogenase major subunit [EC:1.17.1.9] | iPath3 |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 224324.aq_1039 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG0243 | All organisms (root) | formate dehydrogenase major subunit [EC:1.17.1.9],nitrate reductase (cytochrome) [EC:1.9.6.1],assimilatory nitrate reductase catalytic subunit [EC:1.7.99.-] |
| COG0243 | Bacteria (superkingdom) | formate dehydrogenase major subunit [EC:1.17.1.9],nitrate reductase (cytochrome) [EC:1.9.6.1],trimethylamine-N-oxide reductase (cytochrome c) [EC:1.7.2.3] |
| AFSXJ | Aquificae (class) | formate dehydrogenase major subunit [EC:1.17.1.9] |
| FM38T | Aquificales (order) | formate dehydrogenase major subunit [EC:1.17.1.9] |
| 8I1UT | Aquificaceae (family) | formate dehydrogenase major subunit [EC:1.17.1.9] |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.