Domains within Schizosaccharomyces pombe 972h- protein UBC1_SCHPO (O74810)

Ubiquitin-conjugating enzyme E2 1

Alternative representations: 1 /

Protein length217 aa
Source databaseUniProt
Identifiers UBC1_SCHPO, O74810

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

UBC1_SCHPO is shown as ubc1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ubc1

Protein UBC1_SCHPO is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04120Ubiquitin mediated proteolysis

KEGG orthologous groups

KONameDescription
K06689UBE2D, UBC4, UBC5ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K04649UBE2K, HIP2, UBC1ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 284812.O74810 in eggNOG.

OGTaxonomic classDescription
FSM2RDikarya (subkingdom)ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
LCOG5078All organisms (root)ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23],ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24],ubiquitin-conjugating enzyme E2 I
KOG0418Eukaryota (superkingdom)ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23],E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27],ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
BKC05Fungi (kingdom)ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
9SN25Ascomycota (phylum)ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
DVFEDTaphrinomycotina (subphylum)ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
7GBZWOpisthokonta (clade)ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23],E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
CE3BGSchizosaccharomyces (genus)ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: