Domains within Schizosaccharomyces pombe 972h- protein POF3_SCHPO (O74991)

F-box/TPR repeat protein pof3

Alternative representations: 1 /

Protein length577 aa
Source databaseUniProt
Identifiers POF3_SCHPO, O74991

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

POF3_SCHPO is shown as pof3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for pof3

Protein POF3_SCHPO is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05020Prion disease

KEGG orthologous groups

KONameDescription
K09553STIP1stress-induced-phosphoprotein 1
K23424TMTCprotein O-mannosyl-transferase [EC:2.4.1.-]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 284812.O74991 in eggNOG.

OGTaxonomic classDescription
LCOG0457All organisms (root)protein O-mannosyl-transferase [EC:2.4.1.-],kinesin light chain,Ca-activated chloride channel homolog
FSK7CDikarya (subkingdom)F-box/TPR repeat protein Pof3,protein DIA2
KOG0548Eukaryota (superkingdom)stress-induced-phosphoprotein 1,tetratricopeptide repeat protein 28,tetratricopeptide repeat protein 12
BK6CDFungi (kingdom)F-box/TPR repeat protein Pof3,protein DIA2
9SUBXAscomycota (phylum)F-box/TPR repeat protein Pof3,protein DIA2
DVDUFTaphrinomycotina (subphylum)F-box/TPR repeat protein Pof3
7NMJCOpisthokonta (clade)F-box/TPR repeat protein Pof3,protein DIA2
CE5CNSchizosaccharomyces (genus)F-box/TPR repeat protein Pof3

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: