Domains within Mus musculus protein VTI1A_MOUSE (O89116)

Vesicle transport through interaction with t-SNAREs homolog 1A

Alternative representations: 1 /

Protein length217 aa
Source databaseUniProt
Identifiers VTI1A_MOUSE, O89116, ENSMUSP00000093644.2, ENSMUSP00000093644, Q545P9
Source gene ENSMUSG00000024983
Alternative splicing A0A286YDF2_MOUSE, Q5FWJ7_MOUSE, VTI1A_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

VTI1A_MOUSE is shown as Vti1a in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Vti1a

Protein VTI1A_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04130SNARE interactions in vesicular transport

KEGG orthologous groups

KONameDescription
K08493VTI1vesicle transport through interaction with t-SNAREs 1

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000093644 in eggNOG.

OGTaxonomic classDescription
LKOG1666All organisms (root)vesicle transport through interaction with t-SNAREs 1,novel plant SNARE,protein LSM14
KOG1666Eukaryota (superkingdom)vesicle transport through interaction with t-SNAREs 1,novel plant SNARE,protein LSM14
HUN30Metazoa (kingdom)vesicle transport through interaction with t-SNAREs 1
94I8PChordata (phylum)vesicle transport through interaction with t-SNAREs 1
5R5PCSarcopterygii (superclass)vesicle transport through interaction with t-SNAREs 1
8YZPXMammalia (class)vesicle transport through interaction with t-SNAREs 1
4RB5DEuarchontoglires (superorder)vesicle transport through interaction with t-SNAREs 1
AI1QIRodentia (order)vesicle transport through interaction with t-SNAREs 1
8DM99Myomorpha (suborder)vesicle transport through interaction with t-SNAREs 1
H6RU4Bilateria (clade)vesicle transport through interaction with t-SNAREs 1
7GSH7Opisthokonta (clade)vesicle transport through interaction with t-SNAREs 1
9FBUFVertebrata (clade)vesicle transport through interaction with t-SNAREs 1
CQD3SMuridae (family)vesicle transport through interaction with t-SNAREs 1
AE3R4Murinae (subfamily)vesicle transport through interaction with t-SNAREs 1
5PF1RMus (genus)vesicle transport through interaction with t-SNAREs 1
HE56DMus (subgenus)vesicle transport through interaction with t-SNAREs 1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: