Domains within Homo sapiens protein VENTX_HUMAN (O95231)

Homeobox protein VENTX

Alternative representations: 1 /

Protein length258 aa
Source databaseUniProt
Identifiers VENTX_HUMAN, O95231, ENSP00000357556.5, ENSP00000357556, Q32MZ3
Source gene ENSG00000151650

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

VENTX_HUMAN is shown as VENTX in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for VENTX

Protein VENTX_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05202Transcriptional misregulation in cancer

KEGG orthologous groups

KONameDescription
K09360BARHLBarH-like

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000357556 in eggNOG.

OGTaxonomic classDescription
LKOG0488All organisms (root)BarH-like,homeobox protein DBX,BarH-like homeobox
KOG0488Eukaryota (superkingdom)BarH-like,homeobox protein DBX,BarH-like homeobox
HW0W4Metazoa (kingdom)homeobox protein Nkx-1,homeobox protein VENTX
94HPPChordata (phylum)homeobox protein Nkx-1,homeobox protein VENTX
5QDHDSarcopterygii (superclass)homeobox protein VENTX
8ZKXPMammalia (class)homeobox protein VENTX
4RMX2Euarchontoglires (superorder)homeobox protein VENTX
4ZTIZPrimates (order)homeobox protein VENTX
985W6Haplorrhini (suborder)homeobox protein VENTX
BVIMTSimiiformes (infraorder)homeobox protein VENTX
9ESANCatarrhini (parvorder)homeobox protein VENTX
9GU3KVertebrata (clade)homeobox protein Nkx-1,homeobox protein VENTX
H6EQGBilateria (clade)homeobox protein Nkx-1,homeobox protein VENTX
7MVF6Opisthokonta (clade)homeobox protein Nkx-1,homeobox protein VENTX
FX1W3Hominoidea (superfamily)homeobox protein VENTX
5MXMCHominidae (family)homeobox protein VENTX
5XXQMHomininae (subfamily)homeobox protein VENTX

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: