Domains within Homo sapiens protein KI20A_HUMAN (O95235)

Kinesin-like protein KIF20A

Alternative representations: 1 /

Protein length890 aa
Source databaseUniProt
Identifiers KI20A_HUMAN, O95235, ENSP00000378356.3, ENSP00000378356, B4DL79, D3DQB6, D6RBN1_HUMAN, D6RBN1, D6R9E4_HUMAN, D6R9E4, A0A2J8LRE3_PANTR, A0A2J8LRE3
Source gene ENSG00000112984
Alternative splicing ENSP00000422928.1, KI20A_HUMAN, O95235-2, ENSP00000424056.1, H0YAC9_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

KI20A_HUMAN is shown as KIF20A in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for KIF20A

Protein KI20A_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05206MicroRNAs in cancer

KEGG orthologous groups

KONameDescription
K10402KIF20kinesin family member 20

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 47 PTMs annotated in this protein:

PTMCount
Phosphorylation40
Ubiquitination6
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein KIF20A.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000378356 in eggNOG.

OGTaxonomic classDescription
LKOG0247All organisms (root)kinesin family member 20,kinesin family member 23,kinesin family member 7
KOG0247Eukaryota (superkingdom)kinesin family member 20,kinesin family member 23,kinesin family member 7
HTV3KMetazoa (kingdom)kinesin family member 20
94WCBChordata (phylum)kinesin family member 20
5R05ZSarcopterygii (superclass)kinesin family member 20
8ZCHAMammalia (class)kinesin family member 20
4R3ZPEuarchontoglires (superorder)kinesin family member 20
4ZTY7Primates (order)kinesin family member 20
98JB5Haplorrhini (suborder)kinesin family member 20
BVB3MSimiiformes (infraorder)kinesin family member 20
9EWXXCatarrhini (parvorder)kinesin family member 20
H55N2Bilateria (clade)kinesin family member 20
7GMXWOpisthokonta (clade)kinesin family member 20,kinesin family member 23,maestro heat-like repeat-containing protein family member 1
9FXFBVertebrata (clade)kinesin family member 20
FXF53Hominoidea (superfamily)kinesin family member 20
5N991Hominidae (family)kinesin family member 20
5XZJ4Homininae (subfamily)kinesin family member 20

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: