Domains within Homo sapiens protein NEU1_HUMAN (P01178)

Oxytocin-neurophysin 1

Alternative representations: 1 /

Protein length125 aa
Source databaseUniProt
Identifiers NEU1_HUMAN, P01178, ENSP00000217386.2, ENSP00000217386, Q3MIG0, X5D7M6_HUMAN, X5D7M6
Source gene ENSG00000101405

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

NEU1_HUMAN is shown as OXT in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for OXT

Protein NEU1_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04080Neuroactive ligand-receptor interaction

KEGG orthologous groups

KONameDescription
K05243OXToxytocin-neurophysin 1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 2 PTMs annotated in this protein:

PTMCount
Proteolytic cleavage1
Amidation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein OXT.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000217386 in eggNOG.

OGTaxonomic classDescription
71ANNAll organisms (root)oxytocin-neurophysin 1,arginine vasopressin
5G4XMEukaryota (superkingdom)oxytocin-neurophysin 1,arginine vasopressin
HV92RMetazoa (kingdom)oxytocin-neurophysin 1,arginine vasopressin
93M8IChordata (phylum)oxytocin-neurophysin 1,arginine vasopressin
5QXNASarcopterygii (superclass)oxytocin-neurophysin 1
8ZFSRMammalia (class)oxytocin-neurophysin 1
4RHU7Euarchontoglires (superorder)oxytocin-neurophysin 1
4ZTJBPrimates (order)oxytocin-neurophysin 1
98CRNHaplorrhini (suborder)oxytocin-neurophysin 1
BVEZPSimiiformes (infraorder)oxytocin-neurophysin 1
9EVGYCatarrhini (parvorder)oxytocin-neurophysin 1
7JJCCOpisthokonta (clade)oxytocin-neurophysin 1,arginine vasopressin
H4QK8Bilateria (clade)oxytocin-neurophysin 1,arginine vasopressin
9GBXIVertebrata (clade)oxytocin-neurophysin 1
FX2GXHominoidea (superfamily)oxytocin-neurophysin 1
5MYF8Hominidae (family)oxytocin-neurophysin 1
5Y117Homininae (subfamily)oxytocin-neurophysin 1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: