Domains within Ovis aries protein GLHA_SHEEP (P01218)

Glycoprotein hormones alpha chain

Alternative representations: 1 /

Protein length120 aa
Source databaseUniProt
Identifiers GLHA_SHEEP, P01218, ENSOARP00000014092.1, ENSOARP00000014092
Source gene ENSOARG00000013153

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Gnathostomata

Predicted functional partners

GLHA_SHEEP is shown as CGA in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CGA

Protein GLHA_SHEEP is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04912GnRH signaling pathway

KEGG orthologous groups

KONameDescription
K08522CGAglycoprotein hormones alpha chain

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9940.ENSOARP00000014092 in eggNOG.

OGTaxonomic classDescription
7163QAll organisms (root)glycoprotein hormones alpha chain
5K8R0Eukaryota (superkingdom)glycoprotein hormones alpha chain
HU9NEMetazoa (kingdom)glycoprotein hormones alpha chain
93M1MChordata (phylum)glycoprotein hormones alpha chain
5QV5MSarcopterygii (superclass)glycoprotein hormones alpha chain
8Z2AWMammalia (class)glycoprotein hormones alpha chain
BQM8RLaurasiatheria (superorder)glycoprotein hormones alpha chain
AX7SUArtiodactyla (order)glycoprotein hormones alpha chain
B62RMPecora (infraorder)glycoprotein hormones alpha chain
7MTJ8Opisthokonta (clade)glycoprotein hormones alpha chain
H6PC3Bilateria (clade)glycoprotein hormones alpha chain
9GM37Vertebrata (clade)glycoprotein hormones alpha chain
7PDGQBovidae (family)glycoprotein hormones alpha chain

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: