Domains within Bos taurus protein B2MG_BOVIN (P01888)

Beta-2-microglobulin

Alternative representations: 1 /

Protein length118 aa
Source databaseUniProt
Identifiers B2MG_BOVIN, P01888, ENSBTAP00000016359.2, ENSBTAP00000016359, Q148G6, Q56K05
Source gene ENSBTAG00000012330

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

B2MG_BOVIN is shown as B2M in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for B2M

Protein B2MG_BOVIN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03030DNA replication
map04612Antigen processing and presentation

KEGG orthologous groups

KONameDescription
K10739RFA2, RPA2replication factor A2
K08055B2Mbeta-2-microglobulin

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9913.ENSBTAP00000016359 in eggNOG.

OGTaxonomic classDescription
LKOG3108All organisms (root)replication factor A2,spindle assembly abnormal protein 6,beta-2-microglobulin
KOG3108Eukaryota (superkingdom)replication factor A2,spindle assembly abnormal protein 6,beta-2-microglobulin
HVQA7Metazoa (kingdom)replication factor A2,beta-2-microglobulin,replication factor A4
94G46Chordata (phylum)beta-2-microglobulin,replication factor A2,replication factor A4
5QF0ISarcopterygii (superclass)beta-2-microglobulin,replication factor A2,replication factor A4
8ZAKKMammalia (class)beta-2-microglobulin,replication factor A2,replication factor A4
BQYZGLaurasiatheria (superorder)beta-2-microglobulin,replication factor A2,replication factor A4
AXE30Artiodactyla (order)beta-2-microglobulin
B6A3ZPecora (infraorder)beta-2-microglobulin
9GSGBVertebrata (clade)beta-2-microglobulin,replication factor A2,replication factor A4
H39QJBilateria (clade)replication factor A2,beta-2-microglobulin,replication factor A4
7M7VIOpisthokonta (clade)replication factor A2,beta-2-microglobulin,replication factor A4
7PIU3Bovidae (family)beta-2-microglobulin
DAUCGBovinae (subfamily)beta-2-microglobulin
AZZT3Bos (genus)beta-2-microglobulin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: