Domains within Rattus norvegicus protein GAST_RAT (P04563)

Gastrin

Alternative representations: 1 /

Protein length104 aa
Source databaseUniProt
Identifiers GAST_RAT, P04563, ENSRNOP00000019863.1, ENSRNOP00000019863
Source gene ENSRNOG00000014740

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Chordata

Predicted functional partners

GAST_RAT is shown as Gast in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Gast

Protein GAST_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04971Gastric acid secretion

KEGG orthologous groups

KONameDescription
K13768GASTgastrin

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 14 PTMs annotated in this protein:

PTMCount
Proteolytic cleavage7
Phosphorylation2
Sulfation2
Pyrrolidone carboxylic acid formation2
Amidation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Gast.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000019863 in eggNOG.

OGTaxonomic classDescription
6TI57All organisms (root)gastrin
5J815Eukaryota (superkingdom)gastrin
HTB8HMetazoa (kingdom)gastrin
94I9HChordata (phylum)gastrin
5R41NSarcopterygii (superclass)gastrin
8ZAW8Mammalia (class)gastrin
4RNNREuarchontoglires (superorder)gastrin
AICU8Rodentia (order)gastrin
8D72JMyomorpha (suborder)gastrin
7I6U5Opisthokonta (clade)gastrin
9FAFXVertebrata (clade)gastrin
H661NBilateria (clade)gastrin
CQ8MEMuridae (family)gastrin
AEDHKMurinae (subfamily)gastrin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: