Domains within Mus musculus protein PTPRC_MOUSE (P06800)

Receptor-type tyrosine-protein phosphatase C

Alternative representations: 1 /

Protein length1293 aa
Source databaseUniProt
Identifiers PTPRC_MOUSE, P06800, ENSMUSP00000138350.1, ENSMUSP00000138350, E9QLT5, Q61812, Q61813, Q61814, Q61815, Q78EF1, S4R1S4, S4R2V1, A1E2H6_MOUSE, A1E2H6, A0A0P6DCP4_9CRUS, A0A0P6DCP4
Source gene ENSMUSG00000026395
Alternative splicing P06800-6, PTPRC_MOUSE, S4R1M0_MOUSE, A0A0A6YXM4_MOUSE, A0A0A6YWF2_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

PTPRC_MOUSE is shown as Ptprc in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ptprc

Protein PTPRC_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04520Adherens junction
map05132Salmonella infection
map04514Cell adhesion molecules

KEGG orthologous groups

KONameDescription
K06478PTPRC, CD45receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K07817PTPRNreceptor-type tyrosine-protein phosphatase N [EC:3.1.3.48]
K05695PTPRF, LARreceptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000138350 in eggNOG.

OGTaxonomic classDescription
LCOG5599All organisms (root)receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48],tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48],tyrosine-protein phosphatase non-receptor type 14/21 [EC:3.1.3.48]
KOG4228Eukaryota (superkingdom)receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48],receptor-type tyrosine-protein phosphatase epsilon [EC:3.1.3.48],receptor-type tyrosine-protein phosphatase A [EC:3.1.3.48]
HW1UQMetazoa (kingdom)receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48],receptor-type tyrosine-protein phosphatase epsilon [EC:3.1.3.48],receptor-type tyrosine-protein phosphatase delta [EC:3.1.3.48]
93RVHChordata (phylum)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
5R3CRSarcopterygii (superclass)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
8ZI8KMammalia (class)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
4RB7IEuarchontoglires (superorder)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
AHYHARodentia (order)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
8DIDNMyomorpha (suborder)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
7GMZJOpisthokonta (clade)receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48],receptor-type tyrosine-protein phosphatase epsilon [EC:3.1.3.48],receptor-type tyrosine-protein phosphatase delta [EC:3.1.3.48]
9GA5GVertebrata (clade)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
H68G8Bilateria (clade)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48],protein-tyrosine phosphatase [EC:3.1.3.48]
CQBA9Muridae (family)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
AEADJMurinae (subfamily)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
5PMPDMus (genus)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
HE8VQMus (subgenus)receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: