Domains within Escherichia coli BW2952 protein RF2_ECOBW (C5A0G3)

Peptide chain release factor 2

Alternative representations: 1 /

Protein length365 aa
Source databaseUniProt
Identifiers W1B2G9_KLEPN, W1B2G9, W1XQN2_9ZZZZ, W1XQN2, RF2_ECODH, B1XEH8, RF2_ECOLI, P07012, P76642, Q2M9V0, A0A2K1RJ48_ECOLX, A0A2K1RJ48, A0A141RFF5_9BACT, A0A141RFF5, V0V2R0_ECOLX, V0V2R0, A0A141RF46_9BACT, A0A141RF46, A0A1K0I1Y3_ECOLX, A0A1K0I1Y3, C5A0G3, RF2_ECOBW

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

RF2_ECOBW is shown as prfB in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for prfB

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 511145.b2891 in eggNOG.

OGTaxonomic classDescription
LCOG1186All organisms (root)peptide chain release factor 2,ribosome-associated protein,peptidyl-tRNA hydrolase ICT1 [EC:3.1.1.29]
COG1186Bacteria (superkingdom)peptide chain release factor 2,ribosome-associated protein,peptide chain release factor
5ZD4NProteobacteria (phylum)peptide chain release factor 2,peptide chain release factor
EREATGammaproteobacteria (class)peptide chain release factor 2,peptide chain release factor
AUJ85Enterobacterales (order)peptide chain release factor 2
7FMUVEnterobacteriaceae (family)peptide chain release factor 2
GBR0AEscherichia coli (species)peptide chain release factor 2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: