Domains within Escherichia coli O157:H7 protein BARA_ECO57 (P0AEC7)

Signal transduction histidine-protein kinase BarA

Alternative representations: 1 /

Protein length918 aa
Source databaseUniProt
Identifiers P26607, P77032, BARA_ECOL6, P0AEC6, BARA_ECOLI, P0AEC5, A0A077ZIK0_TRITR, A0A077ZIK0, A0A2K0Q0K3_SHIFL, A0A2K0Q0K3, A0A024KQ64_ECOLX, A0A024KQ64, A0A222QQ71_ECOLX, A0A222QQ71, W1ANQ9_KLEPN, W1ANQ9, A0A2H1BGR8_ECOLX, A0A2H1BGR8, A0A1S6TF25_ECOLX, A0A1S6TF25, A0A236MBI6_SHIBO, A0A236MBI6, A0A0H9YBR4_SHISO, A0A0H9YBR4, C3SX37_ECOLX, C3SX37, A0A0J3YQF3, A0A1Z3V0B5_ECOLX, A0A1Z3V0B5, A0A080IU29_ECOLX, A0A080IU29, I4SNF9_ECOLX, I4SNF9, A0A025D1V2_ECOLX, A0A025D1V2, C8UAB8_ECO10, C8UAB8, A0A023Z251_ECOLX, A0A023Z251, A0A073H7I4_ECOLX, A0A073H7I4, M9GWV3_ECOLX, M9GWV3, K4XJM7_ECOLX, K4XJM7, T9TJB8_ECOLX, T9TJB8, Q32CC9_SHIDS, Q32CC9, S1IKV6_ECOLX, S1IKV6, D8E1R8_ECOLX, D8E1R8, A0A080FM73_ECOLX, A0A080FM73, A0A074HR03_ECOLX, A0A074HR03, L4J2Q0_ECOLX, L4J2Q0, A0A1X3JD23_ECOLX, A0A1X3JD23, L2VKR4_ECOLX, L2VKR4, U9ZDF0_ECOLX, U9ZDF0, A0A073UV96_ECOLX, A0A073UV96, V2SVX9_ECOLX, V2SVX9, V6FSK2_ECOLX, V6FSK2, D6ICL7_ECOLX, D6ICL7, A7ZQM9_ECO24, A7ZQM9, L3P2P3_ECOLX, L3P2P3, K0WY59_SHIFL, K0WY59, A0A070UQF4_ECOLX, A0A070UQF4, T9DKU1_ECOLX, T9DKU1, F4NJE8_ECOLX, F4NJE8, A0A1X3IWD5_ECOLX, A0A1X3IWD5, A0A1E3N5S7_9ENTR, A0A1E3N5S7, S0XW21_ECOLX, S0XW21, A0A1X3IJC3_ECOLX, A0A1X3IJC3, A0A1X3I2B3_ECOLX, A0A1X3I2B3, A0A0H3PNI6_ECO5C, A0A0H3PNI6, B2TZE7_SHIB3, B2TZE7, F4V5C7_ECOLX, F4V5C7, S0VC75_ECOLX, S0VC75, A0A064TC34_ECOLX, A0A064TC34, A0A0A8UIM9_ECOLX, A0A0A8UIM9, A0A090NEK9_SHIDY, A0A090NEK9, G0F3V8_ECOLX, G0F3V8, A0A0E1M5C1_ECOLX, A0A0E1M5C1, A0A0E0V957_ECOLX, A0A0E0V957, T5ZSE1_ECOLX, T5ZSE1, D6JEB8_ECOLX, D6JEB8, V8KBX4_ECOLX, V8KBX4, V0A1H9_ECOLX, V0A1H9, V0SVZ8_ECOLX, V0SVZ8, U9XJ26_ECOLX, U9XJ26, A0A1E2VRM0_9ENTR, A0A1E2VRM0, I6FMA9_SHIDY, I6FMA9, E1IQM1_ECOLX, E1IQM1, V0YDT7_ECOLX, V0YDT7, A0A0A0FII8_ECOLX, A0A0A0FII8, Q3YY70_SHISS, Q3YY70, A0A0F6FBG2_ECO57, A0A0F6FBG2, E2X9G9_SHIDY, E2X9G9, S1HKX5_ECOLX, S1HKX5, A0A026VBA3_ECOLX, A0A026VBA3, A0A0G3KAV9_ECOLX, A0A0G3KAV9, A0A069XFL0_ECOLX, A0A069XFL0, I2SNL9_ECOLX, I2SNL9, V2RAN2_ECOLX, V2RAN2, A0A0F6C8A2_ECOLX, A0A0F6C8A2, B1LQX7_ECOSM, B1LQX7, I0VU20_ECOLX, I0VU20, B7N720_ECOLU, B7N720, L3QG89_ECOLX, L3QG89, I2XAT2_ECOLX, I2XAT2, V0YWA3_ECOLX, V0YWA3, A0A0K9TFM0_ECOLX, A0A0K9TFM0, A0A028EBH8_ECOLX, A0A028EBH8, I2WWH3_ECOLX, I2WWH3, E9TMK6_ECOLX, E9TMK6, A0A1S9KB46_SHIDY, A0A1S9KB46, A0A070FEU4_ECOLX, A0A070FEU4, L2XHI9_ECOLX, L2XHI9, T8J8B7_ECOLX, T8J8B7, A0A073FTD7_ECOLX, A0A073FTD7, E6BG03_ECOLX, E6BG03, A0A0M7NCY9_9BURK, A0A0M7NCY9, T5UCP3_ECOLX, T5UCP3, A0A125WYY7_ECOLX, A0A125WYY7, T9AZE4_ECOLX, T9AZE4, A0A1X3LF71_ECOLX, A0A1X3LF71, W1EWL0_ECOLX, W1EWL0, D6I0A9_ECOLX, D6I0A9, I6DTA9_SHIBO, I6DTA9, U9Y706_ECOLX, U9Y706, A0A0E0U2J7_ECOLX, A0A0E0U2J7, S1ER82_ECOLX, S1ER82, A0A0E1STH7_ECOLX, A0A0E1STH7, D3QPY5_ECOCB, D3QPY5, A0A1X3LRW7_ECOLX, A0A1X3LRW7, S0YLC8_ECOLX, S0YLC8, T6LM78_ECOLX, T6LM78, E1J8A8_ECOLX, E1J8A8, E3PHU3_ECOH1, E3PHU3, A0A0E0XWS8_ECO1C, A0A0E0XWS8, D7XU94_ECOLX, D7XU94, F4VHY6_ECOLX, F4VHY6, V0VFG6_ECOLX, V0VFG6, I2RZ52_ECOLX, I2RZ52, H4UN44_ECOLX, H4UN44, D7X6T9_ECOLX, D7X6T9, A0A1X3KZC9_ECOLX, A0A1X3KZC9, D7ZMP4_ECOLX, D7ZMP4, B6I6I2_ECOSE, B6I6I2, W1WK27_9ZZZZ, W1WK27, A0A0A6ZZ21_SHIDY, A0A0A6ZZ21, BARA_ECO57, P0AEC7

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Proteobacteria

Predicted functional partners

BARA_ECO57 is shown as barA in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for barA

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 199310.c3349 in eggNOG.

OGTaxonomic classDescription
LCOG3850All organisms (root)two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3],two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3],two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
LCOG0642All organisms (root)two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3]
LCOG0784All organisms (root)two-component system, chemotaxis family, chemotaxis protein CheY,two-component system, chemotaxis family, chemotaxis protein CheV,two-component system, sensor histidine kinase [EC:2.7.13.3]
LCOG2198All organisms (root)two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3],histidine phosphotransfer protein HptB
71XZ0All organisms (root)two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
COG0784Bacteria (superkingdom)two-component system, chemotaxis family, chemotaxis protein CheY,two-component system, chemotaxis family, chemotaxis protein CheV,two-component system, sensor histidine kinase [EC:2.7.13.3]
COG2198Bacteria (superkingdom)two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3],histidine phosphotransfer protein HptB
COG3850Bacteria (superkingdom)two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3],two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3],two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
COG4999Bacteria (superkingdom)two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
COG0642Bacteria (superkingdom)two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3]
63FPCProteobacteria (phylum)methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],two-component system, sensor histidine kinase [EC:2.7.13.3]
ESDPYGammaproteobacteria (class)two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3],diguanylate cyclase [EC:2.7.7.65],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
AUU81Enterobacterales (order)two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
7FDMNEnterobacteriaceae (family)two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
GBURBEscherichia coli (species)two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: