Domains within Arabidopsis thaliana protein ATX2_ARATH (P0CB22)

Histone-lysine N-methyltransferase ATX2

Alternative representations: 1 /

Protein length1083 aa
Source databaseUniProt
Identifiers Q8RXL4, Q9MA43, ATX2_ARATH, P0CB22

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Arabidopsis thaliana

Predicted functional partners

ATX2_ARATH is shown as ATX2 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ATX2

Protein ATX2_ARATH is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map00310Lysine degradation iPath3
Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

KONameDescription
K07117K07117uncharacterized protein
K11422SETD1, SET1[histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 1 PTMs annotated in this protein:

PTMCount
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ATX2.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 3702.P0CB22 in eggNOG.

OGTaxonomic classDescription
LCOG2940All organisms (root)uncharacterized protein,[histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357],[histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
KOG1080Eukaryota (superkingdom)[histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354],[histone H3]-lysine4 N-trimethyltransferase ATXR3 [EC:2.1.1.354]
G0GZTViridiplantae (kingdom)SET,zf-HC5HC2H_2,PWWP
GFI4VStreptophyta (phylum)PWWP,SET,zf-HC5HC2H_2
C9C1NStreptophytina (subphylum)PWWP,SET,zf-HC5HC2H_2
DGZ33Magnoliopsida (class)PWWP,SET,FYRC
7SSGCBrassicaceae (family)PWWP,FYRN,FYRC
9BBE8Camelineae (tribe)PWWP,FYRN,FYRC

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: