Domains within Cryptococcus neoformans var. neoformans B-3501A protein DPOE_CRYNB (P0CN27)

DNA polymerase epsilon catalytic subunit A

Alternative representations: 1 /

Protein length2250 aa
Source databaseUniProt
Identifiers Q55JX3, Q5K9M7, DPOE_CRYNJ, P0CN26, DPOE_CRYNB, P0CN27

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

DPOE_CRYNB is shown as POL2 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for POL2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 214684.P0CN26 in eggNOG.

OGTaxonomic classDescription
FQ9ZWDikarya (subkingdom)DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
LCOG0417All organisms (root)DNA polymerase, archaea type [EC:2.7.7.7],DNA polymerase epsilon subunit 1 [EC:2.7.7.7],DNA polymerase delta subunit 1 [EC:2.7.7.7]
KOG1798Eukaryota (superkingdom)DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
BP1STFungi (kingdom)DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
CS533Basidiomycota (phylum)DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
DKDKEAgaricomycotina (subphylum)DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
7E8HRTremellomycetes (class)DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
54QNTTremellales (order)DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
7P52ZOpisthokonta (clade)DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
FZG3VCryptococcaceae (family)DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
AEF5XCryptococcus (genus)DNA polymerase epsilon subunit 1 [EC:2.7.7.7]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: