Domains within Bos taurus protein IBP2_BOVIN (P13384)

Insulin-like growth factor-binding protein 2

Alternative representations: 1 /

Protein length317 aa
Source databaseUniProt
Identifiers O97599, A0JGW5_BOVIN, A0JGW5, IBP2_BOVIN, P13384

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Chordata

Predicted functional partners

IBP2_BOVIN is shown as IGFBP2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for IGFBP2

Protein IBP2_BOVIN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04935Growth hormone synthesis, secretion and action

KEGG orthologous groups

KONameDescription
K23577IGFBP5insulin-like growth factor-binding protein 5

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9913.ENSBTAP00000007349 in eggNOG.

OGTaxonomic classDescription
73QK8All organisms (root)insulin-like growth factor-binding protein 5,insulin-like growth factor-binding protein 3,insulin-like growth factor-binding protein 1
5JCMBEukaryota (superkingdom)insulin-like growth factor-binding protein 5,insulin-like growth factor-binding protein 3,insulin-like growth factor-binding protein 1
HVAXEMetazoa (kingdom)insulin-like growth factor-binding protein 2
94T0UChordata (phylum)insulin-like growth factor-binding protein 2
5R3AISarcopterygii (superclass)insulin-like growth factor-binding protein 2
8Z47VMammalia (class)insulin-like growth factor-binding protein 2
BQDWHLaurasiatheria (superorder)insulin-like growth factor-binding protein 2
AX1IZArtiodactyla (order)insulin-like growth factor-binding protein 2
B63HRPecora (infraorder)insulin-like growth factor-binding protein 2
7MEA6Opisthokonta (clade)insulin-like growth factor-binding protein 2
9FZ0YVertebrata (clade)insulin-like growth factor-binding protein 2
H39N4Bilateria (clade)insulin-like growth factor-binding protein 2
7PCBTBovidae (family)insulin-like growth factor-binding protein 2
DB9YNBovinae (subfamily)insulin-like growth factor-binding protein 2
AZGW9Bos (genus)insulin-like growth factor-binding protein 2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: