Domains within Rattus norvegicus protein H14_RAT (P15865)

Histone H1.4

Alternative representations: 1 /

Protein length219 aa
Source databaseUniProt
Identifiers H14_RAT, P15865, ENSRNOP00000066786.1, ENSRNOP00000066786
Source gene ENSRNOG00000047459

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

H14_RAT is shown as H1f4 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for H1f4

Protein H14_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04217Necroptosis
map05146Amoebiasis
map05034Alcoholism

KEGG orthologous groups

KONameDescription
K11275H1_5histone H1/5

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000066786 in eggNOG.

OGTaxonomic classDescription
LKOG4012All organisms (root)histone H1/5,T-cell surface glycoprotein CD1,MHC class I antigen
KOG4012Eukaryota (superkingdom)histone H1/5,T-cell surface glycoprotein CD1,MHC class I antigen
HSQ9UMetazoa (kingdom)histone H1/5,histone H2B,histone H2A
944Y3Chordata (phylum)histone H1/5,histone H2B,histone H2A
5R03SSarcopterygii (superclass)histone H1/5,histone H2B,histone H2A
8YU1IMammalia (class)histone H1/5,histone H2B,histone H2A
4RMSHEuarchontoglires (superorder)histone H1/5,histone H2B,histone H2A
AI1G9Rodentia (order)histone H1/5,histone H2A
8D7QIMyomorpha (suborder)histone H1/5,histone H2A
7J3FSOpisthokonta (clade)histone H1/5,histone H2B,histone H3
9FUVUVertebrata (clade)histone H1/5,histone H2B,histone H2A
H6YDXBilateria (clade)histone H1/5,histone H2B,histone H2A
CQ47UMuridae (family)histone H1/5
AEB1WMurinae (subfamily)histone H1/5

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: