Domains within Mus musculus protein ZFP58_MOUSE (P16372)

Zinc finger protein 58

Alternative representations: 1 /

Protein length489 aa
Source databaseUniProt
Identifiers ZFP58_MOUSE, P16372, ENSMUSP00000132285.1, ENSMUSP00000132285, ENSMUSP00000075487.5, ENSMUSP00000075487, Q3TS54, Q6P8L3, Q7M6X1, Q8BRV1, E9PY65_MOUSE, E9PY65, E9Q218_MOUSE, E9Q218
Source gene ENSMUSG00000071291
Alternative splicing ZFP58_MOUSE, ENSMUSP00000089108.2, ENSMUSP00000129177.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Amniota

Predicted functional partners

ZFP58_MOUSE is shown as Zfp58 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Zfp58

Protein ZFP58_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05168Herpes simplex virus 1 infection

KEGG orthologous groups

KONameDescription
K09228KRABKRAB domain-containing zinc finger protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000075487 in eggNOG.

OGTaxonomic classDescription
LKOG1721All organisms (root)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
KOG1721Eukaryota (superkingdom)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
HU5VDMetazoa (kingdom)KRAB domain-containing zinc finger protein
94S3SChordata (phylum)KRAB domain-containing zinc finger protein
5QRNTSarcopterygii (superclass)KRAB domain-containing zinc finger protein
8ZGSUMammalia (class)KRAB domain-containing zinc finger protein
4R3IDEuarchontoglires (superorder)KRAB domain-containing zinc finger protein
AHXQCRodentia (order)KRAB domain-containing zinc finger protein
8DM4UMyomorpha (suborder)KRAB domain-containing zinc finger protein
9FVY8Vertebrata (clade)KRAB domain-containing zinc finger protein
7MTDYOpisthokonta (clade)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
H6AG8Bilateria (clade)KRAB domain-containing zinc finger protein
CQ0SJMuridae (family)KRAB domain-containing zinc finger protein
AEDH0Murinae (subfamily)KRAB domain-containing zinc finger protein
5PUGCMus (genus)KRAB domain-containing zinc finger protein
HE5ASMus (subgenus)KRAB domain-containing zinc finger protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: