Domains within Bordetella pertussis Tohama I protein BVGS_BORPE (P16575)
Virulence sensor protein BvgS
Alternative representations: 1 /
| Protein length | 1238 aa |
|---|---|
| Source database | UniProt |
| Identifiers | P16576, A0A131HSS5_BORPT, A0A131HSS5, A0A0T7MDQ3_BORPT, A0A0T7MDQ3, BVGS_BORPE, P16575 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
This domain architecture was probably invented with the emergence of Proteobacteria
Predicted functional partners
BVGS_BORPE is shown as 
bvgS in the network
Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.
The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Protein BVGS_BORPE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:
KEGG orthologous groups
| KO | Name | Description | |
|---|---|---|---|
| K02484 | K02484 | two-component system, OmpR family, sensor kinase [EC:2.7.13.3] | |
| K03406 | mcp | methyl-accepting chemotaxis protein | |
| K07679 | evgS, bvgS | two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3] | |
| K02030 | ABC.PA.S | polar amino acid transport system substrate-binding protein | |
| K11527 | K11527 | two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] | |
| K03413 | cheY | two-component system, chemotaxis family, chemotaxis protein CheY |
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 257313.BP1877 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG0642 | All organisms (root) | two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3] |
| LCOG0784 | All organisms (root) | two-component system, chemotaxis family, chemotaxis protein CheY,two-component system, chemotaxis family, chemotaxis protein CheV,two-component system, sensor histidine kinase [EC:2.7.13.3] |
| LCOG2202 | All organisms (root) | methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],aerotaxis receptor |
| LCOG0834 | All organisms (root) | polar amino acid transport system substrate-binding protein,L-cystine transport system substrate-binding protein,general L-amino acid transport system substrate-binding protein |
| COG0784 | Bacteria (superkingdom) | two-component system, chemotaxis family, chemotaxis protein CheY,two-component system, chemotaxis family, chemotaxis protein CheV,two-component system, sensor histidine kinase [EC:2.7.13.3] |
| COG0834 | Bacteria (superkingdom) | polar amino acid transport system substrate-binding protein,L-cystine transport system substrate-binding protein,general L-amino acid transport system substrate-binding protein |
| COG0642 | Bacteria (superkingdom) | two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3] |
| COG2202 | Bacteria (superkingdom) | methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],aerotaxis receptor |
| 63FPC | Proteobacteria (phylum) | methyl-accepting chemotaxis protein,diguanylate cyclase [EC:2.7.7.65],two-component system, sensor histidine kinase [EC:2.7.13.3] |
| 8UE3B | Betaproteobacteria (class) | two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3] |
| GH3SJ | Burkholderiales (order) | two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3] |
| A4ZZI | Alcaligenaceae (family) | two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3] |
| 87KXM | Bordetella (genus) | two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3] |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.