Domains within Rattus norvegicus protein PSA3_RAT (P18422)

Proteasome subunit alpha type-3

Alternative representations: 1 /

Protein length255 aa
Source databaseUniProt
Identifiers PSA3_RAT, P18422, ENSRNOP00000010753.4, ENSRNOP00000010753, G1SZ14_RABIT, G1SZ14
Source gene ENSRNOG00000007851

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

PSA3_RAT is shown as Psma3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Psma3

Protein PSA3_RAT is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05016Huntington disease
map03050Proteasome

KEGG orthologous groups

KONameDescription
K02727PSMA320S proteasome subunit alpha 7 [EC:3.4.25.1]
K03433psmB, prcBproteasome beta subunit [EC:3.4.25.1]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Phosphorylation3
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Psma3.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10116.ENSRNOP00000010753 in eggNOG.

OGTaxonomic classDescription
LCOG0638All organisms (root)proteasome beta subunit [EC:3.4.25.1],20S proteasome subunit beta 2 [EC:3.4.25.1],20S proteasome subunit alpha 4 [EC:3.4.25.1]
KOG0184Eukaryota (superkingdom)20S proteasome subunit alpha 7 [EC:3.4.25.1]
HVZM3Metazoa (kingdom)20S proteasome subunit alpha 7 [EC:3.4.25.1]
94MUVChordata (phylum)20S proteasome subunit alpha 7 [EC:3.4.25.1]
5QSYSSarcopterygii (superclass)20S proteasome subunit alpha 7 [EC:3.4.25.1]
8ZIPKMammalia (class)20S proteasome subunit alpha 7 [EC:3.4.25.1]
4R1TBEuarchontoglires (superorder)20S proteasome subunit alpha 7 [EC:3.4.25.1]
AI8J0Rodentia (order)20S proteasome subunit alpha 7 [EC:3.4.25.1]
8D4VBMyomorpha (suborder)20S proteasome subunit alpha 7 [EC:3.4.25.1]
H3VYUBilateria (clade)20S proteasome subunit alpha 7 [EC:3.4.25.1]
7MNS2Opisthokonta (clade)20S proteasome subunit alpha 7 [EC:3.4.25.1]
9G4J0Vertebrata (clade)20S proteasome subunit alpha 7 [EC:3.4.25.1]
CQFWVMuridae (family)20S proteasome subunit alpha 7 [EC:3.4.25.1]
AE7ZXMurinae (subfamily)20S proteasome subunit alpha 7 [EC:3.4.25.1]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: