Domains within Bos taurus protein ADCY1_BOVIN (P19754)

Adenylate cyclase type 1

Alternative representations: 1 /

Protein length1134 aa
Source databaseUniProt
Identifiers ADCY1_BOVIN, P19754

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

ADCY1_BOVIN is shown as ADCY1 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ADCY1

Protein ADCY1_BOVIN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04024cAMP signaling pathway
map00230Purine metabolism iPath3
Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

KONameDescription
K08042ADCY2adenylate cyclase 2 [EC:4.6.1.1]
K08041ADCY1adenylate cyclase 1 [EC:4.6.1.1]
K01768E4.6.1.1adenylate cyclase [EC:4.6.1.1]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9913.ENSBTAP00000012528 in eggNOG.

OGTaxonomic classDescription
LCOG2114All organisms (root)adenylate cyclase [EC:4.6.1.1],guanylate cyclase soluble subunit beta [EC:4.6.1.2],PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
KOG3619Eukaryota (superkingdom)adenylate cyclase 2 [EC:4.6.1.1],adenylate cyclase 1 [EC:4.6.1.1],adenylate cyclase 8 [EC:4.6.1.1]
HTIM7Metazoa (kingdom)adenylate cyclase 2 [EC:4.6.1.1],adenylate cyclase 8 [EC:4.6.1.1],adenylate cyclase 1 [EC:4.6.1.1]
94EHRChordata (phylum)adenylate cyclase 1 [EC:4.6.1.1]
5QYUSSarcopterygii (superclass)adenylate cyclase 1 [EC:4.6.1.1]
8Z3YAMammalia (class)adenylate cyclase 1 [EC:4.6.1.1]
BQKYVLaurasiatheria (superorder)adenylate cyclase 1 [EC:4.6.1.1]
AXE5ZArtiodactyla (order)adenylate cyclase 1 [EC:4.6.1.1]
B67IWPecora (infraorder)adenylate cyclase 1 [EC:4.6.1.1]
7NRDPOpisthokonta (clade)adenylate cyclase 2 [EC:4.6.1.1],adenylate cyclase 8 [EC:4.6.1.1],adenylate cyclase 1 [EC:4.6.1.1]
9FF1WVertebrata (clade)adenylate cyclase 1 [EC:4.6.1.1]
H50FGBilateria (clade)adenylate cyclase 1 [EC:4.6.1.1],adenylate cyclase 8 [EC:4.6.1.1],adenylate cyclase 2 [EC:4.6.1.1]
7PVRXBovidae (family)adenylate cyclase 1 [EC:4.6.1.1]
DB95GBovinae (subfamily)adenylate cyclase 1 [EC:4.6.1.1]
AZW6JBos (genus)adenylate cyclase 1 [EC:4.6.1.1]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: