Domains within Escherichia coli K-12 protein NADR_ECOLI (P27278)
Trifunctional NAD biosynthesis/regulator protein NadR
Alternative representations: 1 /
| Protein length | 410 aa |
|---|---|
| Source database | UniProt |
| Identifiers | P76819, Q2M5S7, A0A1X3J871_ECOLX, A0A1X3J871, C3SE32_ECOLX, C3SE32, A0A2H1BQ45_ECOLX, A0A2H1BQ45, A0A024L890_ECOLX, A0A024L890, A0A0J3WCX8, A0A1S9JF47_SHIBO, A0A1S9JF47, A0A025CK44_ECOLX, A0A025CK44, A0A023Z7C3_ECOLX, A0A023Z7C3, L3BUV3_ECOLX, L3BUV3, V2S5R0_ECOLX, V2S5R0, D6IHU7_ECOLX, D6IHU7, S0WAK2_ECOLX, S0WAK2, L2XWS4_ECOLX, L2XWS4, A0A0M7NIK4_9BURK, A0A0M7NIK4, T5TQJ8_ECOLX, T5TQJ8, L4USM7_ECOLX, L4USM7, NADR_ECOLI, P27278 |
Domain architecture analysis
Display all proteins with similar:
| Domain organisation | Proteins having all the domains as the query in the same order. Additional domains are allowed. |
|---|---|
| Domain composition | Proteins with the same domain composition have at least one copy of each of the domains of the query. |
This domain architecture was probably invented with the emergence of cellular organisms
Predicted functional partners
NADR_ECOLI is shown as 
nadR in the network
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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.
Orthologous groups
Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 511145.b4390 in eggNOG.
| OG | Taxonomic class | Description |
|---|---|---|
| LCOG3172 | All organisms (root) | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22],pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] |
| LCOG1396 | All organisms (root) | XRE family transcriptional regulator, fatty acid utilization regulator,XRE family transcriptional regulator, regulator of sulfur utilization,HTH-type transcriptional regulator / antitoxin HipB |
| LCOG1056 | All organisms (root) | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22],nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1],bifunctional NMN adenylyltransferase/nudix hydrolase [EC:2.7.7.1 3.6.1.-] |
| COG3172 | Bacteria (superkingdom) | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22],pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] |
| COG1056 | Bacteria (superkingdom) | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22],bifunctional NMN adenylyltransferase/nudix hydrolase [EC:2.7.7.1 3.6.1.-],8-oxo-dGTP diphosphatase [EC:3.6.1.55] |
| COG1396 | Bacteria (superkingdom) | XRE family transcriptional regulator, fatty acid utilization regulator,XRE family transcriptional regulator, regulator of sulfur utilization,HTH-type transcriptional regulator / antitoxin HipB |
| 635NA | Proteobacteria (phylum) | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22] |
| ET774 | Gammaproteobacteria (class) | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22] |
| AUKJN | Enterobacterales (order) | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22] |
| 7FNA4 | Enterobacteriaceae (family) | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22] |
| GBSUW | Escherichia coli (species) | HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22] |
The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.