Domains within Mus musculus protein RXRG_MOUSE (P28705)

Retinoic acid receptor RXR-gamma

Alternative representations: 1 /

Protein length463 aa
Source databaseUniProt
Identifiers RXRG_MOUSE, P28705, ENSMUSP00000015987.3, ENSMUSP00000015987, ENSMUSP00000107017.1, ENSMUSP00000107017, ENSMUSP00000107015.1, ENSMUSP00000107015, Q3V193_MOUSE, Q3V193, Q6LDB2_9MURI, Q6LDB2, E9Q9V9_MOUSE, E9Q9V9
Source gene ENSMUSG00000015843
Alternative splicing RXRG_MOUSE, ENSMUSP00000107011.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Metazoa

Predicted functional partners

RXRG_MOUSE is shown as Rxrg in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Rxrg

Protein RXRG_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03320PPAR signaling pathway
map05200Pathways in cancer

KEGG orthologous groups

KONameDescription
K08526RXRG, NR2B3retinoid X receptor gamma
K08524RXRA, NR2B1retinoid X receptor alpha
K08554NR3B3, ESRRGestrogen-related receptor gamma

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 3 PTMs annotated in this protein:

PTMCount
Phosphorylation3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Rxrg.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000015987 in eggNOG.

OGTaxonomic classDescription
LKOG3575All organisms (root)estrogen-related receptor gamma,nuclear receptor subfamily 2 group E member 3,retinoid X receptor alpha
KOG3575Eukaryota (superkingdom)estrogen-related receptor gamma,nuclear receptor subfamily 2 group E member 3,retinoid X receptor alpha
HSURJMetazoa (kingdom)retinoid X receptor alpha,nuclear receptor subfamily 1 group D member 2,retinoid X receptor gamma
93KEUChordata (phylum)retinoid X receptor gamma,retinoid X receptor alpha,retinoid X receptor beta
5QP94Sarcopterygii (superclass)retinoid X receptor gamma,retinoid X receptor alpha,retinoid X receptor beta
8Z15RMammalia (class)retinoid X receptor gamma,retinoid X receptor alpha
4R5B2Euarchontoglires (superorder)retinoid X receptor gamma
AI1Q8Rodentia (order)retinoid X receptor gamma
8DGRMMyomorpha (suborder)retinoid X receptor gamma
H5DKEBilateria (clade)retinoid X receptor alpha,retinoid X receptor gamma,retinoid X receptor beta
9GJGWVertebrata (clade)retinoid X receptor gamma,retinoid X receptor alpha,retinoid X receptor beta
7IRHVOpisthokonta (clade)retinoid X receptor alpha,nuclear receptor subfamily 1 group D member 2,retinoid X receptor gamma
CQBMKMuridae (family)retinoid X receptor gamma
AEDCRMurinae (subfamily)retinoid X receptor gamma
5PM94Mus (genus)retinoid X receptor gamma
HE049Mus (subgenus)retinoid X receptor gamma

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: