Domains within Mus musculus protein TNFL8_MOUSE (P32972)

Tumor necrosis factor ligand superfamily member 8

Alternative representations: 1 /

Protein length239 aa
Source databaseUniProt
Identifiers TNFL8_MOUSE, P32972, ENSMUSP00000030047.2, ENSMUSP00000030047, Q544U1_MOUSE, Q544U1, Q3U033_MOUSE, Q3U033
Source gene ENSMUSG00000028362

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

TNFL8_MOUSE is shown as Tnfsf8 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Tnfsf8

Protein TNFL8_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04060Cytokine-cytokine receptor interaction

KEGG orthologous groups

KONameDescription
K05471TNFSF8, CD153tumor necrosis factor ligand superfamily member 8

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000030047 in eggNOG.

OGTaxonomic classDescription
6ZGBMAll organisms (root)tumor necrosis factor ligand superfamily member 8
5JF24Eukaryota (superkingdom)tumor necrosis factor ligand superfamily member 8
HVWGMMetazoa (kingdom)tumor necrosis factor ligand superfamily member 8
93IB7Chordata (phylum)tumor necrosis factor ligand superfamily member 8
5QNKFSarcopterygii (superclass)tumor necrosis factor ligand superfamily member 8
8YUQAMammalia (class)tumor necrosis factor ligand superfamily member 8
4R2X1Euarchontoglires (superorder)tumor necrosis factor ligand superfamily member 8
AIE7PRodentia (order)tumor necrosis factor ligand superfamily member 8
8DEJ0Myomorpha (suborder)tumor necrosis factor ligand superfamily member 8
7JKTAOpisthokonta (clade)tumor necrosis factor ligand superfamily member 8
H4Q90Bilateria (clade)tumor necrosis factor ligand superfamily member 8
9GFJTVertebrata (clade)tumor necrosis factor ligand superfamily member 8
CQ0CDMuridae (family)tumor necrosis factor ligand superfamily member 8
AEDC0Murinae (subfamily)tumor necrosis factor ligand superfamily member 8
5PRY6Mus (genus)tumor necrosis factor ligand superfamily member 8
HEA7KMus (subgenus)tumor necrosis factor ligand superfamily member 8

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: