Domains within Saccharomyces cerevisiae S288C protein HSP78_YEAST (P33416)

Heat shock protein 78, mitochondrial

Alternative representations: 1 /

Protein length811 aa
Source databaseUniProt
Identifiers D6VSN8, Q12137, C7GTJ3_YEAS2, C7GTJ3, E7QD40_YEASZ, E7QD40, E7KB28_YEASA, E7KB28, C8Z5H0_YEAS8, C8Z5H0, N1P535_YEASC, N1P535, E7KLV2_YEASL, E7KLV2, B5VGE2_YEAS6, B5VGE2, E7LT00_YEASV, E7LT00, A0A0L8VTM2_9SACH, A0A0L8VTM2, HSP78_YEAST, P33416

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

HSP78_YEAST is shown as HSP78 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for HSP78

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Acetylation3
Phosphorylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_44750.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YDR258C in eggNOG.

OGTaxonomic classDescription
FT0XJDikarya (subkingdom)ATP-dependent Clp protease ATP-binding subunit ClpB
LCOG0542All organisms (root)ATP-dependent Clp protease ATP-binding subunit ClpB,ATP-dependent Clp protease ATP-binding subunit ClpC,ATP-dependent Clp protease ATP-binding subunit ClpA
KOG1051Eukaryota (superkingdom)ATP-dependent Clp protease ATP-binding subunit ClpB,ATP-dependent Clp protease ATP-binding subunit ClpC
BM1YBFungi (kingdom)ATP-dependent Clp protease ATP-binding subunit ClpB
9SRFIAscomycota (phylum)ATP-dependent Clp protease ATP-binding subunit ClpB
91C92Saccharomycetales (order)ATP-dependent Clp protease ATP-binding subunit ClpB
7M7D2Opisthokonta (clade)ATP-dependent Clp protease ATP-binding subunit ClpB
AT5F7Saccharomycetaceae (family)ATP-dependent Clp protease ATP-binding subunit ClpB

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: