Domains within Saccharomyces cerevisiae YJM789 protein YEL1_YEAS7 (A6ZKN8)

Guanine-nucleotide exchange factor YEL1

Alternative representations: 1 /

Protein length687 aa
Source databaseUniProt
Identifiers YEL1_YEAS8, C8Z3N7, YEL1_YEAST, P34225, D6VPT9, YEL1_YEAS7, A6ZKN8

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Fungi/Metazoa group

Predicted functional partners

YEL1_YEAS7 is shown as YEL1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for YEL1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 13 PTMs annotated in this protein:

PTMCount
Phosphorylation13

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_20420.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YBL060W in eggNOG.

OGTaxonomic classDescription
LKOG0929All organisms (root)brefeldin A-inhibited guanine nucleotide-exchange protein,F-box protein 8,guanine nucleotide-exchange factor
FPY9DDikarya (subkingdom)PH and SEC7 domain-containing protein
KOG0929Eukaryota (superkingdom)brefeldin A-inhibited guanine nucleotide-exchange protein,F-box protein 8,guanine nucleotide-exchange factor
BPUSIFungi (kingdom)PH and SEC7 domain-containing protein
7MANJOpisthokonta (clade)PH and SEC7 domain-containing protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: