Domains within Mus musculus protein FGF7_MOUSE (P36363)

Fibroblast growth factor 7

Alternative representations: 1 /

Protein length194 aa
Source databaseUniProt
Identifiers FGF7_MOUSE, P36363, ENSMUSP00000069681.7, ENSMUSP00000069681, ENSMUSP00000106072.1, ENSMUSP00000106072, Q544I6_MOUSE, Q544I6
Source gene ENSMUSG00000027208

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

FGF7_MOUSE is shown as Fgf7 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Fgf7

Protein FGF7_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05224Breast cancer
map04020Calcium signaling pathway

KEGG orthologous groups

KONameDescription
K04358FGFfibroblast growth factor

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Phosphorylation2
Acetylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Fgf7.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000069681 in eggNOG.

OGTaxonomic classDescription
LKOG3885All organisms (root)fibroblast growth factor,fibroblast growth factor 11/12/13,fibroblast growth factor 1
KOG3885Eukaryota (superkingdom)fibroblast growth factor,fibroblast growth factor 11/12/13,fibroblast growth factor 1
HUZ5QMetazoa (kingdom)fibroblast growth factor
93MYMChordata (phylum)fibroblast growth factor
5R72VSarcopterygii (superclass)fibroblast growth factor
8YVN3Mammalia (class)fibroblast growth factor
4RJ57Euarchontoglires (superorder)fibroblast growth factor
AI43ARodentia (order)fibroblast growth factor
8D7U1Myomorpha (suborder)fibroblast growth factor
7H7JROpisthokonta (clade)fibroblast growth factor,fibroblast growth factor 11/12/13,fibroblast growth factor 1
9G6G7Vertebrata (clade)fibroblast growth factor
H6XZEBilateria (clade)fibroblast growth factor
CQ4GMMuridae (family)fibroblast growth factor
AED9KMurinae (subfamily)fibroblast growth factor
5PVP8Mus (genus)fibroblast growth factor
HE2YWMus (subgenus)fibroblast growth factor

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: