Domains within Drosophila melanogaster protein CIN_DROME (P39205)

Molybdenum cofactor synthesis protein cinnamon

Alternative representations: 1 /

Protein length601 aa
Source databaseUniProt
Identifiers CIN_DROME, P39205, FBPP0070063, FBPP0070064, Q0KHX9, Q9U1M0, Q9V3E2, E4NKI3_DROME, E4NKI3, Q6W4E3_DROME, Q6W4E3
Source gene FBgn0000316

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

CIN_DROME is shown as cin in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for cin

Protein CIN_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map00790Folate biosynthesis iPath3
Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

KONameDescription
K03750moeAmolybdopterin molybdotransferase [EC:2.10.1.1] iPath3
K15376GPHNgephyrin [EC:2.10.1.1 2.7.7.75] iPath3
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 1 PTMs annotated in this protein:

PTMCount
Phosphorylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein cin.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0070064 in eggNOG.

OGTaxonomic classDescription
LCOG0303All organisms (root)molybdopterin molybdotransferase [EC:2.10.1.1],gephyrin [EC:2.10.1.1 2.7.7.75],putative molybdopterin biosynthesis protein
EJ0J8Endopterygota (cohort)gephyrin [EC:2.10.1.1 2.7.7.75]
FUXG5melanogaster group (species group)gephyrin [EC:2.10.1.1 2.7.7.75]
FE0XXmelanogaster subgroup (species subgroup)gephyrin [EC:2.10.1.1 2.7.7.75]
KOG2371Eukaryota (superkingdom)gephyrin [EC:2.10.1.1 2.7.7.75],molybdopterin molybdotransferase [EC:2.10.1.1],renalase [EC:1.6.3.5]
HTZG9Metazoa (kingdom)gephyrin [EC:2.10.1.1 2.7.7.75]
HIG2WArthropoda (phylum)gephyrin [EC:2.10.1.1 2.7.7.75]
85UU0Hexapoda (subphylum)gephyrin [EC:2.10.1.1 2.7.7.75]
AHFV7Neoptera (infraclass)gephyrin [EC:2.10.1.1 2.7.7.75]
ANCRZDiptera (order)gephyrin [EC:2.10.1.1 2.7.7.75]
H4UB5Bilateria (clade)gephyrin [EC:2.10.1.1 2.7.7.75]
7M6ZWOpisthokonta (clade)gephyrin [EC:2.10.1.1 2.7.7.75],molybdopterin molybdotransferase [EC:2.10.1.1]
EH37EDrosophila (genus)gephyrin [EC:2.10.1.1 2.7.7.75]
50JSTSophophora (subgenus)gephyrin [EC:2.10.1.1 2.7.7.75]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: