Domains within Saccharomyces cerevisiae S288C protein RPAB4_YEAST (P40422)

DNA-directed RNA polymerases I, II, and III subunit RPABC4

Alternative representations: 1 /

Protein length70 aa
Source databaseUniProt
Identifiers D3DL93, C7GXW4_YEAS2, C7GXW4, G2WFL7_YEASK, G2WFL7, J8QFG5_SACK1, J8QFG5, C8Z9U1_YEAS8, C8Z9U1, A0A0L8VPG4_9SACH, A0A0L8VPG4, N1P4S0_YEASC, N1P4S0, J8Q167_SACAR, J8Q167, A0A250WKW1_YEASX, A0A250WKW1, B3LSQ8_YEAS1, B3LSQ8, RPAB4_YEAST, P40422

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

RPAB4_YEAST is shown as RPC10 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RPC10

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 1 PTMs annotated in this protein:

PTMCount
Phosphorylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein EC1118_1H13_1178g.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YHR143W-A in eggNOG.

OGTaxonomic classDescription
FRT2CDikarya (subkingdom)DNA-directed RNA polymerases I, II, and III subunit RPABC4
LKOG3507All organisms (root)DNA-directed RNA polymerase subunit P [EC:2.7.7.6],DNA-directed RNA polymerases I, II, and III subunit RPABC4,ATP-dependent helicase Lhr and Lhr-like helicase [EC:3.6.4.13 5.6.2.4]
KOG3507Eukaryota (superkingdom)DNA-directed RNA polymerases I, II, and III subunit RPABC4
BKZHVFungi (kingdom)DNA-directed RNA polymerases I, II, and III subunit RPABC4
9SDJ9Ascomycota (phylum)DNA-directed RNA polymerases I, II, and III subunit RPABC4
91EHRSaccharomycetales (order)DNA-directed RNA polymerases I, II, and III subunit RPABC4
7HUHEOpisthokonta (clade)DNA-directed RNA polymerases I, II, and III subunit RPABC4
AT7PMSaccharomycetaceae (family)DNA-directed RNA polymerases I, II, and III subunit RPABC4

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: